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A new mutation linked to partial Androgen Insensitivity Syndrome and prostate cancer was found in a patient unhappy with their female gender assignment.

Syphilis is becoming more common and remains a major health problem due to challenges in prevention and treatment.

Hormonal changes and psychological issues can cause sexual dysfunction in postmenopausal women. Behavioral therapy is recommended first, with hormone replacement helping some symptoms but not libido. Testosterone can improve libido, but its effects on overall sexual function are unclear. Emotional and relationship issues should be addressed before using medication, and the benefits and risks of testosterone supplementation should be considered.

Adult acne is often mild and common on the cheek, with a low prevalence of PCOS in female patients, but more severe acne and skin damage in those with PCOS.

Topical minoxidil helps transgender individuals assigned female at birth grow more facial hair.

iPSCs can help treat genetic skin disorders by creating healthy skin cells from a small biopsy.

Self-amplifying RNA could be a better option for protein replacement therapy with lower doses and lasting effects, but delivering it into cells is still challenging.

The guideline provides healthcare professionals in South Africa with instructions for comprehensive, multidisciplinary gender-affirming care, including HIV prevention and treatment for transgender and gender diverse individuals.

Fat-derived stem cells show promise for treating skin issues and improving wound healing, but more research is needed to confirm the best way to use them.

More personalized and effective treatments for androgenetic alopecia are needed.

Short-acting testosterone injections in a clinic are a preferred treatment for low testosterone because they work well, are convenient, and patients stick with the treatment.

Triamcinolone acetonide injections effectively treat skin disorders like eczema and psoriasis.

Alopecia areata incognito in children can be effectively treated with triamcinolone acetonide and supplements, leading to full hair regrowth.

A toddler with a rash and developmental delays improved after treatment for severe malnutrition caused by a diet lacking in protein.

Injection lipolysis effectively reduces small fat deposits and should be done with care and proper patient selection.

Injecting 2 ml of TEEV every 4 weeks is better because it has the same benefits but fewer side effects.

Intramuscular triamcinolone acetonide is an effective treatment for severe alopecia areata, especially in males.

PRP injections increase hair density and diameter in female androgenetic alopecia patients.

Ivermectin injections and spray, along with hygiene measures, successfully treated sarcoptic mange in guinea pigs.

Methotrexate injection site reactions are rare but can be managed by changing injection sites and using topical treatments.

The document concludes that inhalation of oxygen and sumatriptan injections are primary for cluster headaches, indomethacin for paroxysmal hemicrania, and lidocaine and lamotrigine for SUNCT, but SUNCT often resists treatment.

Substance abuse can cause various skin problems, including marks from injections, sores, premature aging, and increased cancer risk.

Vitamin B12 deficiency can cause skin darkening and increased blood vessels, but treatment can improve symptoms.

Tiny particles from stem cells help activate hair growth cells and encourage hair growth in mice without being toxic.

Treatments for permanent hair loss from scarring aim to stop further loss, not regrow hair, and vary by condition, with partial success common.

Sumatriptan injections, high-flow oxygen, and verapamil effectively treat cluster headaches.

The document concludes that there are various treatments for different types of alopecia, but more research is needed for evidence-based treatments.

Reflectance confocal microscopy helped diagnose and manage a woman's hair loss without needing a biopsy.

Vitamin D is crucial for health, and deficiency can cause hair loss and other health issues.

Dupilumab for skin problems might reactivate hair loss in some patients.