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Some common medications can harm male fertility, but many effects can be reversed.

Testosterone replacement can help women with low libido and mood, but they need to have enough estrogen first to avoid side effects.

Hormone treatment for transgender patients may not need to be stopped before surgery, but more research is needed, especially on estrogen.

Androgen therapy can help with symptoms like low libido in women, but more research is needed to understand its long-term safety and effects on health.

Hormone therapy is safe and effective for transgender adults, but requires regular monitoring and mental health support.

Hormone therapy for trans individuals is effective and generally safe in the short term.

Hormone treatments for transgender individuals generally improve mental health and physical transition, with some health risks that require medical supervision.

The conclusion is that published guidelines are improving transgender medical care, but more research and education in transgender medicine are needed.

Cross-sex hormone therapy is important for managing gender dysphoria and requires careful monitoring and healthcare provider education.

5α-reductase inhibitors like finasteride may not be effective or safe for transgender individuals, and more research is needed.

Hormone therapy may increase migraines in transgender women and decrease them in transgender men; more research is needed on migraine management in transgender individuals.

Pre-operative hormone treatment for hypospadias surgery might improve outcomes, but more research is needed to confirm.

Hormone treatment before hypospadias surgery can increase penis size and reduce surgery complications.

A 19-year-old male with delayed puberty was successfully treated for a condition that prevents normal hormone production.

Muscles can make their own androgens, which may help muscle growth.

The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.

The guideline provides healthcare professionals in South Africa with instructions for comprehensive, multidisciplinary gender-affirming care, including HIV prevention and treatment for transgender and gender diverse individuals.

Gender-affirming hormone therapy improves physical performance in trans men to the level of cisgender men, while in trans women, it increases fat mass and decreases muscle mass, with no advantage in physical performance after 2 years.

Gender-affirming hormone therapy changes hair growth in transgender people, with feminizing therapy reducing hair and masculinizing therapy increasing it, but sometimes additional treatment is needed.

AGA treatments like minoxidil and LLLLT are safe and effective for gender minority patients.

Finasteride may cause long-lasting sexual side effects.

Testing for CAG repeat polymorphism in the androgen receptor gene is not currently recommended for managing hypogonadism.

The guidelines recommend informed consent for gender-affirming treatments and stress the importance of personalized, culturally sensitive care for transgender individuals.

Hormone therapy increases facial and body hair in transgender men, while hair removal improves well-being in transgender women, but cost is a barrier as insurance often doesn't cover it. Dermatologists can use various treatments for these hair issues.

Enobosarm significantly increased muscle mass and improved physical function in elderly men and postmenopausal women without serious side effects.

Topical minoxidil helps transgender individuals assigned female at birth grow more facial hair.

Exogenous testosterone use may be linked to developing hidradenitis suppurativa.

New treatments for male hypogonadism are effective and should be personalized.

Early medical support for transgender youth is important for their health, with low regret for gender-affirming hormone use and a need for knowledgeable care providers.

Androgen therapy might help some women with low libido, but it has risks and should be used carefully.