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Scientists successfully created and analyzed the structure of a part of the human androgen receptor with specific modulators and a peptide to understand how it binds differently in various tissues.

The meeting highlighted the complexity and variability of skin conditions and differing opinions on their diagnoses and treatments.

Tretinoin gel is safe for sun exposure, but tacalcitol doesn't significantly improve non-segmental vitiligo.

Testosterone therapy improves physical function, strength, and body composition in older men with low testosterone levels.

The article suggests managing interferon beta therapy side effects in MS with dose adjustments, medications, and patient education.

Interferon alfa-2a is effective for treating cutaneous T cell lymphoma but has significant side effects.

Lichen planus is a skin condition that can resolve on its own, is linked to hepatitis C, and increases the risk of skin cancer.

Testosterone treatment in trans men increases body and facial hair and may lead to hair loss over time, but severe skin issues are rare.

Testosterone supplements can increase muscle mass and strength in older men with low levels, but long-term effects and risks need more research.

Testosterone therapy seems safe for postmenopausal women for a few years, but more research is needed for long-term effects.

Testosterone with or without finasteride doesn't improve thinking skills in older men with low testosterone.

Minoxidil and finasteride are effective for male hair loss, minoxidil for female hair loss, and various treatments like corticosteroids work for alopecia areata; treatment should be tailored to the individual.

Shrinking skin cancer increases the chance of cancer in nearby lymph nodes.

Using CRISPR for gene editing in the body is promising but needs better delivery methods to be more efficient and specific.

Hormone treatment for transgender patients may not need to be stopped before surgery, but more research is needed, especially on estrogen.

Antiandrogens, particularly flutamide and CPA, are most effective for treating hirsutism, with long-term use needed for best results.

Testosterone therapy is generally safe for transmen, improves sexual function, and has manageable health risks with proper monitoring.

Both treatments for pemphigus foliaceus in dogs are effective, but combination therapy has more side effects.

Certain hormone treatments can improve acne and related conditions in women.

Subcutaneous contraceptives can cause side effects like menstrual changes, headaches, weight gain, and pain at the implant site.

Testosterone therapy and surgeries like mastectomy improve transgender men's lives and mental health with low risks and high satisfaction.

New drugs for heart disease may be developed from molecules secreted by stem cells.

Some patients receiving pegylated interferon alfa injections developed skin necrosis, requiring treatment adjustments or discontinuation.

PRP injections increase hair density and diameter in female androgenetic alopecia patients.

Methotrexate for rheumatoid arthritis often causes side effects like diarrhea, fatigue, and hair loss, especially at higher doses.

Birth control pills can help manage acne, but dermatologists should know their skin-related side effects, especially when prescribing drugs that can harm unborn babies.

The conclusion is that removing both ovaries is the best treatment for excess male hormones in postmenopausal women, with medication as another option, and managing insulin resistance is important for diagnosis and treatment.

In Japan, sex reassignment surgery for gender identity disorder faces challenges and needs better medical support and education.

The document concludes that managing side effects of MS therapies is crucial for treatment success and patient adherence.

Teriflunomide is an effective and safe first-line oral treatment for relapsing multiple sclerosis.