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A substance called Compound 2g can strongly block STS (a hormone-related enzyme) without affecting estrogen levels, making it potentially good for treating breast cancer.

Adding a second method to PROTACs could improve cancer treatment.

Certain genes and pathways are linked to the production of finer and denser wool in Hetian sheep.

Human hair keratins K85 and K35 create unique filament patterns important for early hair formation.

Scalp flaps are stiffer than skin from other body areas, which helps in planning reconstructive and cosmetic head surgeries.

The document concludes that there are still unknowns about the effectiveness, risks, and detection of performance-enhancing drugs, and doping remains a challenge.

Angora goat hair grows faster and produces more protein than cashmere goat hair, and certain hormones and nutrients positively affect hair growth and protein synthesis.

Using an enzyme and keratin treatment can significantly repair and strengthen damaged hair.

Minoxidil does not work to inhibit lysyl hydroxylases in newborn mouse lungs.

The nucleus is key in controlling skin growth and repair by coordinating signals, gene regulators, and epigenetic changes.

Understanding wool keratin-associated proteins in sheep can help improve wool quality through selective breeding.

Combining DHT and EDC improves the strength and stability of PADM scaffolds for tissue engineering.

Hard skin features like scales, feathers, and hair evolved through specific protein changes in different animal groups.

Scientists discovered a unique hair protein, KAP24.1, with a special structure, found only in the upper part of hair cuticles.

New ginseng compounds may help treat degenerative diseases.

Mutations at Val-889 and Arg-752 disrupt key interactions in the androgen receptor, affecting its function.

Permanent wave treatment with thioglycolic acid changes hair structure by altering disulfide bonds.

Changes in keratin make hair follicles stiffer.

Researchers found that the most reachable bonds in wool fibers are near the ends of certain proteins, which help stabilize the fiber's structure.

Washing permed hair after using thioglycolic acid helps reform strong bonds, making hair stronger.

Minoxidil decreases LH expression, while hydralazine has mixed effects on prolyl and lysyl hydroxylase activities.

Minoxidil slows fibroblast growth and collagen production, potentially treating keloids, hypertrophic scars, and connective tissue disorders.

Minoxidil reduces lysine hydroxylase in skin cells.

Minoxidil needs specific structure to block lysyl hydroxylase; exploring alternatives may keep benefits without this effect.

Minoxidil slows down skin cell growth and may help treat scars and skin conditions.

Hair and nail cells share similar proteins, indicating a common differentiation pathway.

New single-cell analysis techniques are improving our understanding of stem cells and could help in treating diseases.

Human beard hair medulla contains a unique and complex mix of keratins not found in other human tissues.

Androgen receptors are key for development and health, affecting conditions like prostate cancer and male pattern baldness.

Permanent waving weakens hair by altering its protein structure.