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Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

Exposure to too much androgen before birth might cause polycystic ovary syndrome later in life.

Melatonin in the skin helps protect against damage from stress and UV rays, and could be used to treat certain skin conditions.

Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.

The document concludes that understanding hair follicle biology can lead to better hair loss treatments.

Chemotherapy causes hair loss by damaging hair follicles and stem cells, with more research needed for prevention and treatment.

Overexpression of activin A in mice skin causes skin thickening, fibrosis, and improved wound healing.

Stress stops hair growth in mice by causing early hair growth phase end and harmful inflammation through a specific nerve-related pathway.

Melatonin may benefit skin health and could be a promising treatment in dermatology.

Alopecia areata is an autoimmune condition causing hair loss due to the immune system attacking hair follicles, often influenced by genetics and stress.

Hair follicle dermal stem cells are key for regenerating parts of the hair follicle and determining hair type.

Hair loss in men is common, treatable, but not curable.

Isotretinoin is highly effective in treating severe acne, rosacea, and gram-negative folliculitis.

Chemotherapy can cause skin problems like hair loss, mouth sores, and skin darkening, and recognizing these can affect treatment decisions.

The conclusion is that accurate diagnosis of different types of hair loss requires good teamwork between skin doctors and lab experts.

Hair follicle stem cells are key for hair and skin regeneration, can be reprogrammed, and have potential therapeutic uses, but also carry a risk of cancer.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

The document concludes that more research is needed to better understand and treat primary cicatricial alopecias, and suggests a possible reclassification based on molecular pathways.

Skin grafts on mice can cause an immune response leading to hair loss, useful for studying human hair loss conditions.

Prolactin contributes to hair loss by promoting hair follicle shrinkage and cell death.

Stress can stop hair growth in mice, and treatments can reverse this effect.

Folliculitis decalvans is a rare scalp condition causing scarring hair loss, treated with long-term antibiotics and other medications, but it often comes back and is hard to manage.

Melatonin helps regulate hair growth and protects the hair follicle from stress.

The document concludes that assessing hair follicle damage due to cyclophosphamide in mice involves analyzing structural changes and suggests a scoring system for standardized evaluation.

Activating TRPV3 stops human hair growth.

MicroRNA-214 is important for skin and hair growth because it affects the Wnt pathway.

Chemotherapy often causes temporary hair loss, which is distressing and needs better treatment and support.

Restoring hair bulb immune privilege is crucial for managing alopecia areata.

Nerves and chemicals in the body can affect hair growth and loss.

Hair loss in men treated best with early medication or transplant, new treatments researched.