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The document concludes that blocking the internal pathways that create androgens might help treat cancers that depend on sex hormones.

Eating high-glycemic foods and drinking milk may worsen acne by increasing insulin and IGF-1 levels.

Men with early balding showed higher levels of certain genes linked to hair loss and possibly prostate cancer.

Human sebaceous glands contain enzymes that affect androgen production and may influence sebum production and acne.

A new method accurately measures nine specific hormones in human blood.

Testosterone helps human pancreatic cells increase insulin release.

The enzyme 5α-reductase type 1 is important for blood vessel development and fertility in the uterus.

The enzyme 5α-reductase is important for proper blood vessel development during the fertility-related transformation of the uterus lining.

Targeting androgen receptors could be a promising way to treat skin disorders with fewer side effects.

Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.

Human skin produces sex hormones like estrogen and testosterone, influenced by ARO and StAR, which may affect skin elasticity and hair growth.

New androgen receptor modulators show promise for treating diseases like prostate cancer and muscle wasting.

The androgen receptor is a promising target for breast cancer treatment, especially in triple-negative cases, but more research is needed for personalized therapies.

Sebocytes play a key role in controlling androgen levels in human skin.

Androgen therapy can help with symptoms like low libido in women, but more research is needed to understand its long-term safety and effects on health.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Certain inhibitors can potentially treat prostate cancer and other hormone-dependent conditions by controlling sex hormone levels in cells.

Acne is a common skin condition linked to diet, hormones, and genetics, and early treatment can prevent scarring.

Chromosomal differences affect how muscle cells respond to testosterone.

SAHA syndrome is a condition in women involving skin and hair issues, often related to hormonal imbalances, and is treated based on the underlying cause.

The protein StAR is found in 17 different organs and can affect hair loss and brain functions, but its full role is not yet fully understood.

Certain drugs that block specific enzymes can help treat prostate diseases.

The document concludes that using LC-MS/MS for measuring androgens is more accurate than older methods, but it needs careful validation and standardized references to be most effective.

Acne can be managed with various treatments and requires psychological support due to its emotional impact.

The conclusion is that endocrinology significantly impacts medicine with various common medications used for treatment.

Hormonal therapy changes skin and hair in transgender patients, who need better researched dermatologic care.

Acne can't be cured but can be managed with treatments like benzoyl peroxide and diet changes; it's costly and can lead to scarring and mental health issues.

The review suggests that while many AKR1C3 inhibitors show promise for treating certain cancers, more research is needed to confirm their effectiveness in humans.

Testosterone can help premenopausal and postmenopausal women with low sexual desire, but its long-term safety is unclear and it's not widely approved for this use.

Hair loss can be caused by stress, aging, and harmful substances that create an imbalance in the body's natural processes.