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Finasteride in male rats causes liver and metabolic issues in their offspring.

Removing part of the vitamin D receptor stops vitamin D from working properly.

The conclusion is that genetic changes in the glucocorticoid receptor can lead to conditions affecting stress response, immunity, and metabolism, requiring personalized treatment.

Impaired androgen production in 46,XY DSDs causes ambiguous genitalia and requires long-term care.

Glutathione helps Arabidopsis roots adapt to low phosphate by regulating a specific growth pathway.

Further research is needed to improve hair regeneration using stem cells and nanomaterials.

Exosomes show promise for tissue repair and regeneration with advantages over traditional cell therapies.

Regulatory T cells help heal skin and grow hair, and their absence can lead to healing issues and hair loss.

CLE40 and CRN/CLV2 pathways have opposite effects on root growth in Arabidopsis.

Stem cells in hair follicles can become various cell types, including neurons.

Eph/ephrin signaling is important for skin cell behavior and could be targeted to treat skin diseases.

CRISPR/Cas9 editing in spinach affects root hair growth by altering specific genes.

Exosomes can help repair and heal tissues, improving health and vitality.

The document concludes that mouse models are helpful but have limitations for skin wound healing research, and suggests using larger animals and genetically modified mice for better human application.

Fatty acid transport protein 4 is essential for skin and hair development.

The cornified envelope is crucial for skin's barrier function and involves key proteins and genetic factors.

Lichen Planus is a less common condition affecting skin and mucous membranes, with various types and associated risk factors, challenging to diagnose, significantly impacts life quality, and may have a risk of cancerous changes in oral lesions.

Artificial skin development has challenges, but new materials and understanding cell behavior could improve tissue repair. Also, certain growth factors and hydrogel technology show promise for advanced skin replacement therapies.

The document concludes that more research is needed to better understand and treat primary cicatricial alopecias, and suggests a possible reclassification based on molecular pathways.

Exosomes could potentially enhance tissue repair and regeneration with lower rejection risk and easier production than live cell therapies.

The skin's internal clock affects healing, cancer risk, aging, immunity, and hair growth, and disruptions can harm skin health.

The circadian clock influences the behavior and regeneration of stem cells in the body.

Melanocyte development from neural crest cells is complex and influenced by many factors, and better understanding could help treat skin disorders.

Mice can correct hair follicle orientation without certain genes, but proper overall alignment needs those genes.

Certain proteins are essential for the growth of root hairs in barley.

Immune cells help regulate hair growth, and better understanding this can improve hair loss treatments.

Cashmere and milk goats have different hair growth cycles and gene expressions, which could help improve wool production.

Over 67 genes linked to ichthyosis help improve diagnosis and treatment.

The document concludes that immune system abnormalities cause alopecia areata, but the exact process is still not completely understood.

Tiny natural vesicles from cells might help treat hair loss.