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Mutations in the SRD5A3 gene cause a new type of glycosylation disorder by blocking the production of a molecule necessary for protein glycosylation.

The document concludes that insulin resistance is key in PCOS development and early treatment is crucial to prevent complications.

Exposure to too much androgen before birth might cause polycystic ovary syndrome later in life.

The immune system plays a key role in tissue repair, affecting both healing quality and regenerative ability.

Melatonin in the skin helps protect against damage from stress and UV rays, and could be used to treat certain skin conditions.

Insulin resistance is a key factor in polycystic ovary syndrome, but genetics may also contribute.

Wnt1/βcatenin signaling is crucial for heart repair after injury.

TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.

Hair loss and aging are caused by the breakdown of a key protein in hair stem cells.

Fat cells help recruit healing cells and build skin structure during wound healing.

A protein from certain immune cells is key for new hair growth after skin injury in mice.

Chitin and chitosan are useful in cosmetics for oral care, haircare, and skincare, including UV protection and strength improvement.

Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.

AGA causes hair loss by shrinking hair follicles due to DHT binding, and can be treated with finasteride and minoxidil.

The conclusion is that proper signaling is crucial for hair growth and development, and errors can lead to cancer or hair loss.

Some patients taking finasteride or dutasteride may have ongoing sexual problems and depression even after stopping the medication.

Eph receptors and ephrins may be promising targets for treating diseases, but more understanding is needed for effective and safe therapies.

Insulin resistance and obesity are key factors in the development and worsening of polycystic ovary syndrome, and lifestyle changes are important for managing it.

Melatonin is important for skin health and protection, and can be made by the skin or applied to it.

Hair color production in mice is closely linked to the hair growth phase and may also influence hair growth itself.

Androgens can both increase and decrease hair growth in different parts of the body.

Skin needs dermal β-catenin activity for hair growth and skin cell multiplication.

Iron deficiency may be related to hair loss, but there's not enough evidence to recommend iron screening or supplements for all hair loss patients.

Overexpression of activin A in mice skin causes skin thickening, fibrosis, and improved wound healing.

Lactate production is important for activating hair growth stem cells.

Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.

Calcium affects where root hairs grow, but other unknown factors determine their growth direction.

Male and female bodies respond differently to stress, influenced by hormones and development stages, with implications for stress-related diseases.

Sebocytes play a key role in controlling androgen levels in human skin.

Dermatologists need to understand hair products to treat hair and scalp issues better.