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Janus Kinase inhibitors are effective and have an acceptable safety profile for treating moderate to severe Ulcerative Colitis.

Dutasteride is more effective than finasteride for hair loss treatment.

Zebrafish with mutations similar to human Cantú Syndrome have heart cells with altered channel properties, making them a good model to study the condition.

Not having enough cystatin M/E protein causes less hair growth and dry skin.

Diet and supplements can significantly affect acne, with some foods and nutrients reducing and others worsening it.

Astrotactin2 affects hair follicle orientation and skin cell polarity.

Different forms of finasteride dissolve and remain stable differently, affecting capsule quality.

Ketogenic diet, neurosteroids, and HMGB1-TLR4 signaling pathway are potential targets for new epilepsy treatments.

Anabolic steroids can build muscle and strength but have risks and need more research on their clinical benefits and side effects.

Keratins help protect cells, aid in cancer diagnosis, and influence cancer behavior and treatment.

Human skin makes sexual hormones that affect hair growth, skin health, and healing; too much can cause acne and hair loss, while treatments can manage these conditions.

Certain proteins, Lgr5 and Lgr6, are important markers of adult stem cells and are involved in tissue repair and cancer development.

Ectodin integrates BMP, SHH, and FGF signals in developing ectodermal organs.

BAY 43-9006 helps control kidney cancer growth but doesn't significantly increase overall survival.

Skin fat cells help with skin balance, hair growth, and healing wounds.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Tiny pollution particles called PM2.5 can harm skin cells by causing stress, damage to cell parts, and cell death.

The hedgehog signaling pathway is crucial for hair growth but not for the initial creation of hair follicles.

Minoxidil sulfate stimulates hair growth.

TGF-β is crucial for controlling stem cell behavior and changes in its signaling can lead to diseases like cancer.

Methotrexate treats various disorders by inhibiting DNA synthesis, but careful monitoring is needed to avoid toxicity and manage side effects.

Estrogen therapy can reduce skin aging but has cancer risks.

Minoxidil boosts hair growth by increasing cell production and survival.

The WNT signaling pathway is important in many diseases and targeting it could offer new treatments.

Modulating BMP activity changes the number, size, shape, and type of ectodermal organs.

Cepharanthine is a well-tolerated drug with multiple medical uses, including anti-inflammatory and anti-cancer properties.

Janus kinase inhibitors are promising treatments for autoimmune skin diseases like eczema and psoriasis.

New targets for making and using brain-synthesized steroids could lead to better treatments for brain disorders and alcoholism.

Understanding how cells die in the skin is important for treating skin diseases and preventing hair loss.

Estrogens help reduce skin aging, and SERMs might offer similar benefits without the risks of hormone therapy.