research A Novel and Safe Small Molecule Enhances Hair Follicle Regeneration by Facilitating Metabolic Reprogramming
Small molecule IM boosts hair growth by changing stem cell metabolism.
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research Tailored Chromatin Modulation to Promote Tissue Regeneration
Understanding and manipulating epigenetic changes can potentially lead to human organ regeneration therapies, but more research is needed to improve these methods and minimize risks.
research Role of Beta-Catenin Activation Levels and Fluctuations in Controlling Cell Fate
Proper control of β-catenin activity is crucial for development and preventing diseases like cancer.
research Dynamic Signals for Hair Follicle Development and Regeneration
Certain signals and genes play a key role in hair growth and regeneration, and understanding these could lead to new treatments for skin regeneration.
research Wnt Signaling: The Good and the Bad
Wnt signaling is important for development and cell regulation but can cause diseases like cancer when not working properly.
research Runx1 Role in Epithelial and Cancer Cell Proliferation Implicates Lipid Metabolism and SCD1 and SOAT1 Activity
Runx1 controls fat-related genes important for normal and cancer cell growth, affecting skin and hair cell behavior.
research Organ Regeneration Based on Developmental Biology: Past and Future
Scientists have made progress in growing mini-organs and regenerating parts of the skin, with plans to treat hair loss in a future trial.
research The Notch Intracellular Domain Has an RBPj-Independent Role During Mouse Hair Follicular Development
The Notch signaling pathway helps in mouse hair development through a noncanonical mechanism that does not rely on RBPj or transcription.
research Wnt/β-Catenin Signaling Promotes Aging-Associated Hair Graying in Mice
A certain signaling pathway in mice, when increased, causes hair to gray by depleting the cells that give hair its color.
research Engineered Skin Substitute Regenerates Skin with Hair Follicle Formation
The engineered skin substitute helped grow skin with hair on mice.
research All Roads Lead to the Nucleus: Integration of Signaling, Transcription Factor-Mediated, and Epigenetic Regulatory Mechanisms in the Control of Skin Development and Regeneration
The nucleus is key in controlling skin growth and repair by coordinating signals, gene regulators, and epigenetic changes.
research Ephrins Negatively Regulate Cell Proliferation in the Epidermis and Hair Follicle
Ephrins slow down skin and hair follicle cell growth.
research Role of Vitamin D and Calcium Signaling in Epidermal Wound Healing
Vitamin D and calcium are important for quick and effective skin wound healing.
research Comparative Biology of Tissue Repair, Regeneration, and Aging
The symposium concluded that understanding how different species repair tissue and how this changes with age can help advance regenerative medicine.
research Wound-Induced Hair Neogenesis: A Novel Paradigm for Studying Regeneration and Aging
Wounds can regenerate hair in young mice, but this ability declines with age, offering insights for improving tissue regeneration in the elderly.
research Molecular Signaling and Nutritional Regulation in the Context of Poultry Feather Growth and Regeneration
Good feather growth in poultry needs the right balance of proteins, amino acids, minerals, and vitamins.
research Cell Fate Decisions: Emerging Roles for Metabolic Signals and Cell Morphology
Metabolic signals and cell shape influence how cells develop and change.
research Mechanical Force Drives the Initial Mesenchymal-Epithelial Interaction During Skin Organoid Development
Mechanical force is important for the first contact between skin cells and hair growth in mini-organs.
research Progenitor-Derived Endothelin Controls Dermal Sheath Contraction for Hair Follicle Regression
A specific signal from hair cells controls the tightening of the surrounding muscle, which is necessary for hair shedding.
research Mucosal TLR5 Activation Controls Healthspan and Longevity
Activating TLR5 in the gut can extend lifespan and improve health in aged mice.
research Trends in the Global Organoid Technology and Industry: From Organogenesis in a Dish to the Commercialization of Organoids
Organoid technology is advancing and entering commercial use, with applications in disease modeling, drug development, and personalized medicine.
research Integrin Signaling Regulates YAP/TAZ to Control Skin Homeostasis
YAP and TAZ are crucial for skin cell growth and repair.
research SOX9 in Organogenesis: Shared and Unique Transcriptional Functions
SOX9 is essential for the development of various organs and hair follicles.
research Regulation and Dysregulation of Hair Regeneration: Aiming for Clinical Application
Understanding hair growth involves complex factors, and more research is needed to improve treatments for hair loss conditions.
research Single-Cell Sequencing Reveals Differential Cell Types in Skin Tissues of Liaoning Cashmere Goats and Key Genes Potentially Related to the Fineness of Cashmere Fiber
Certain genes are linked to the quality of cashmere in goats.
research TLR2 Regulates Hair Follicle Cycle and Regeneration via BMP Signaling
TLR2 helps control hair growth and regeneration, and its reduction with age or obesity can impair hair growth.
research Role of Regeneration in Tissue Repairing and Therapies
The review concludes that innovations in regenerative medicine, tissue engineering, and developmental biology are essential for effective tissue repair and organ transplants.
research Partial Proteasome Inhibitors Induce Hair Follicle Growth by Stabilizing Beta-Catenin
Certain inhibitors applied to the skin can promote hair growth by maintaining a key hair growth signal.
research What Does the Concept of the Stem Cell Niche Really Mean Today?
Stem cell niches support, regulate, and coordinate stem cell functions.
research Blimp1+ Cells Generate Functional Mouse Sebaceous Gland Organoids In Vitro
Single Blimp1+ cells can create functional sebaceous gland organoids in the lab.