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Scientists have improved 3D models of human skin for research and medical uses, but still face challenges in perfectly replicating real skin.

Adult hair follicle cells can create new hair follicles from corneal cells with the right support.

The environment around melanocyte stem cells is key for hair regeneration and color, with certain injuries affecting hair color and potential treatments for pigmentation disorders.

Cell death shapes skin stem cell environments, affecting inflammation, repair, and cancer.

Different small areas within hair follicles send specific signals that control what type of cells stem cells become.

Epigenetic changes control how adult stem cells work and can lead to diseases like cancer if they go wrong.

Live imaging has advanced our understanding of stem cell behavior and raised new research questions.

Different stem cells are key for hair growth and health, and understanding their regulation could help treat hair loss.

β-catenin is essential for stem cell activation and proliferation in hair follicles.

The document concludes that both internal stem cell factors and external influences like the environment and hormones affect hair loss and aging, with potential treatments focusing on these areas.

Skin stem cells interacting with their environment is crucial for maintaining and regenerating skin and hair, and understanding this can help develop new treatments for skin and hair disorders.

Skin stem cells are maintained by signals from nearby cells and vary in their ability to renew and mature.

Special immune cells called Treg cells are important for maintaining and regenerating hair by activating a specific growth signal in hair stem cells.

Hair follicles and deer antlers regenerate similarly through stem cells and are influenced by hormones and growth factors.

Radiation mainly affects keratinocyte stem cells, not melanocyte stem cells, causing hair to gray.

Lung repair involves both dedicated and flexible stem cells, important for developing new treatments.

Researchers created a fully functional, bioengineered skin system with hair from stem cells that successfully integrated when transplanted into mice.

Skin can produce blood cells, often due to disease, which might lead to new treatments for skin and blood conditions.

Removing the ATR gene in adult mice causes rapid aging and stem cell loss.

New single-cell analysis techniques are improving our understanding of stem cells and could help in treating diseases.

The document concludes that adult mammalian skin contains multiple stem cell populations with specific markers, important for understanding skin regeneration and related conditions.

Inactive hair follicle stem cells help prevent skin cancer.

Eating less can slow aging and help keep stem cells healthy by cleaning out damaged cell parts.

Stem cells help remove dead cells to keep tissues healthy by balancing cell replacement and clearance.

Maintaining DNA integrity in stem cells is crucial to prevent aging and cancer.

Dermal papilla cells are key for hair growth and color, influencing hair type and size, and their interaction with stem cells could help treat hair loss and color disorders.

Inflammation plays a key role in activating skin stem cells for hair growth and wound healing, but more research is needed to understand how it directs cell behavior.

CD4+ skin cells may be precursors to basal cell carcinoma.

Skin aging is due to impaired stem cell mobilization or fewer responsive stem cells.

Human hair follicle stem cells can turn into multiple cell types but lose some of this ability after being grown in the lab for a long time.