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The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.

Different types of long-lasting stem cells are responsible for the growth and upkeep of the mammary gland.

Proteasome inhibitors are promising treatments for various cancers, autoimmune diseases, and other conditions.

Stromal stem cells may help heal wounds by becoming structural cells or affecting the immune system, but more research is needed to understand how.

Androgens can both increase and decrease hair growth in different parts of the body.

Different types of skin cells have unique genetic markers that affect how likely they are to spread cancer.

Telocytes might help with skin repair and regeneration.

Liposomal systems show promise for delivering drugs through the skin but face challenges like high costs and stability issues.

Pig skin is a good substitute for human skin to measure drug absorption, but differences in skin structure and enzymes across species must be considered.

The conclusion is that the increasing use of drugs for lifestyle reasons is a complex issue influenced by corporate profit, consumer behavior, and the medicalization of everyday life, with potential negative effects on personal well-being.

Androgens can both stimulate and cause hair loss, and understanding their effects is key to treating hair disorders.

The sebaceous gland has more roles than just producing sebum and contributing to acne, and new research could lead to better skin disease treatments.

Mutant CDP/Cux protein causes hair defects and reduced male fertility in mice.

Fetal skin heals without scarring due to unique cells and processes not present in adult skin healing.

The document concludes that rapid identification, isolation, and strict infection control are crucial to manage SARS outbreaks.

Iron deficiency common in women, not always linked to hair loss; more research needed.

Wnt signaling may be linked to heart diseases in aging and could be a target for future treatments.

Drugs targeting the JAK/STAT pathway can improve atopic dermatitis but vary in effectiveness for vitiligo and alopecia areata, with generally mild safety concerns.

People with PCNT mutations often develop severe insulin resistance and early-onset diabetes during childhood or adolescence.

Insulin resistance linked to obesity may increase COVID-19 severity.

Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.

Disrupting Acvr1b in mice causes severe hair loss and thicker skin.

Lymphatic vessels are essential for hair follicle growth and skin regeneration.

Nano-sized plant-based chemicals could improve cervical cancer treatment by being more effective and causing fewer side effects than current methods.

Advancements in creating skin grafts with biomaterials and stem cells are promising, but more research is needed for clinical application.

CRAC channels are crucial for the development and function of specialized immune cells, preventing severe inflammation and autoimmune diseases.

S100A3 protein is crucial for hair shaft formation in mice.

Skin organoids are a promising new model for studying human skin development and testing treatments.

Stem cells and their surrounding environment in hair follicles work closely together, affecting hair growth and having implications for cancer and tissue regeneration.

The document concludes that menopause should be seen as a natural part of aging and managed with personalized care and informed choices.