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Finasteride in male rats causes liver and metabolic issues in their offspring.

The document suggests a new way to categorize skin and mind disorders into two main groups to reduce confusion.

The skin has multiple layers and cells, serves as a protective barrier, helps regulate temperature, enables sensation, affects appearance, and is involved in vitamin D synthesis.

Diet and supplements can significantly affect acne, with some foods and nutrients reducing and others worsening it.

Isotretinoin effectively treats severe acne and similar conditions, but has common, mostly reversible side effects, requiring careful patient monitoring.

People with PCNT mutations often develop severe insulin resistance and early-onset diabetes during childhood or adolescence.

Researchers created a new mouse model for studying Citrullinemia Type I and similar conditions, showing symptoms and treatment responses like those in humans.

Single-cell engineered biotherapeutics show promise for skin treatment but need more research and trials.

The essential oils from Hedyotis corymbosa, Inula racemose, and Holostemma adakodien have significant antibacterial and antifungal properties.

Lower LDL-c levels predict higher COVID-19 mortality.

People with atopic dermatitis have different skin bacteria, and targeting these bacteria might help treat the condition.

Staphylococcus epidermidis A/C strains are more antibiotic-resistant and infection-adapted, while B strains thrive in hair follicles.

Tamarix aphylla may be effective for various medical conditions, but more research is needed to confirm its safety and effectiveness.

Marine algae compounds may improve skin health and promote hair growth.

Your skin is like an ecosystem, with its own community of microbes and substances that interact and affect its health.

Environmental factors can cause mutations in skin proteins, leading to skin disorders.

Cerasus serrulata flower extracts have strong antibacterial and antioxidant effects and may help prevent hair loss.

Most over-the-counter hair loss treatments lack strong evidence of effectiveness but cost nearly as much as the proven treatment, minoxidil.

Finasteride can have lasting negative effects on brain function and behavior by disrupting neurosteroid production.

FLRG and follistatin have different roles in wound healing.

Cavity macrophages gather on organ surfaces but don't really invade or help repair the organs after injury.

Melatonin, usually known for sleep regulation, also has antioxidant properties that can protect skin, stimulate hair growth, and improve skin conditions, with topical application being more effective than oral use.

The Bcl-2 protein is important for keeping hair follicle stem cells working and preventing hair loss.

Low and ultralow doses of flutamide can cause liver damage in young women with high androgen levels, regardless of dose or birth control use, with higher risk for those with higher BMI and liver enzyme levels before treatment.

Mesenchymal Stem Cells (MSCs) are promising for multiple therapies, but more research is needed to fully understand and optimize their use.

The Drug Ontology was updated to better classify drugs for hypertension, malaria, and opioid abuse, and to allow for more accurate research queries.

Skin stem cells are crucial for maintaining and repairing skin, with potential for treating skin disorders and improving wound healing.

The document concludes that better targeted treatments are needed for wound healing, and single-cell technologies may improve cell-based therapies.

The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.

Proteasome inhibitors are promising treatments for various cancers, autoimmune diseases, and other conditions.