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Eating less can improve stem cell function and increase lifespan.

Metabolism plays a key role in determining stem cell fate.

Hair chemicals don't cause SLE but may increase skin issues in those with SLE.

Understanding and manipulating epigenetic changes can potentially lead to human organ regeneration therapies, but more research is needed to improve these methods and minimize risks.

The document concludes that understanding how the skin's immune system and inflammation work is complex and requires more research to improve treatments for skin diseases.

Skin stem cells are maintained by signals from nearby cells and vary in their ability to renew and mature.

Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.

Hair can regrow after certain stem cells are lost because other stem cells can take over their role.

RANK is a key target in breast cancer treatment due to its role in tumor growth and bone metastasis.

Hoxc genes control hair growth through Wnt signaling.

High levels of the protein Flightless I worsen ulcerative colitis symptoms in mice.

Putting α-methylspermidine on mouse skin can start hair growth.

New techniques have enhanced our understanding of how stem cells function and the role of mutations in aging tissues, which may influence future cancer therapies.

Dermal papilla cells are key for hair growth and color, influencing hair type and size, and their interaction with stem cells could help treat hair loss and color disorders.

Humans have limited regenerative abilities, but new evidence shows the adult brain and heart can regenerate, and future treatments may improve this by mimicking stem cell environments.

The vitamin D receptor is involved in multiple body functions beyond calcium regulation, including immune response and rapid reactions not related to gene activity.

Epithelial stem cells are crucial for tissue renewal and repair, and understanding them could improve treatments for damage and cancer.

Stem cells help heal skin wounds by moving and changing roles, working with other cells, and needing more research on their activation and behavior.

Early development of hair, teeth, and glands involves specific signaling pathways and cellular interactions.

The niche environment controls stem cell behavior and plasticity, which is important for tissue health and repair.

Matriptase is crucial for keeping epithelial tissues healthy and functioning properly.

MicroRNA-214 is important for skin and hair growth because it affects the Wnt pathway.

β-Catenin signaling is involved in brain cell growth after injury and could be a therapy target.

Isotretinoin's effects and side effects, like birth defects and depression, might be due to it causing cell death in various cells.

Human alpha defensin 5 helps heal wounds, reduce bacteria, and grow hair on burned skin.

In vivo lineage labelling is better than in vitro methods for identifying and understanding stem cells.

The document concludes that stem cell inactivity is actively controlled and important for tissue repair and balance.

Hair follicles and deer antlers regenerate similarly through stem cells and are influenced by hormones and growth factors.

The vitamin D receptor has many roles in the body beyond managing calcium, affecting the immune system, hair growth, muscles, fat, bone marrow, and cancer cells.

Mice without the vitamin D receptor have bone issues and other health problems, suggesting vitamin D is important for preventing various diseases in humans.