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The conditions alopecia areata, primary sclerosing cholangitis, and ulcerative colitis may be linked by shared autoimmune and cell death mechanisms.

Lichen planopilaris in men often involves scalp redness and itching, with some also having hair loss, mucosal lichen planus, or thyroid disease, and treatment improved symptoms in nearly half of the cases.

Cell transplantation faces challenges in genitourinary reconstruction, but alternative tissue sources and microencapsulation show promise.

Keratin 18 helps diagnose and predict cancer progression and affects cancer growth and spread.

The study found that certain genes are important for hedgehog skin appendage development and immunity, with spines possibly evolving for protection and infection resistance.

A high-fat diet caused severe health problems in female macaques but was reversible with a normal diet, while male macaques reacted differently.

The document concludes that accurate diagnosis of male and female gonadal disorders is crucial for effective treatment and better patient outcomes.

The secretions of mesenchymal stem cells could be used for healing without using the cells themselves.

Melatonin affects many body functions beyond sleep by interacting with specific receptors in various tissues.

Hair follicles help absorb and store topical compounds, aiding targeted drug delivery.

Skin needs dermal β-catenin activity for hair growth and skin cell multiplication.

Alopecia areata is an autoimmune condition causing hair loss due to the immune system attacking hair follicles, often influenced by genetics and stress.

Stress-related substance P may lead to hair loss and negatively affect hair growth.

The document concludes that recognizing and treating cutaneous lupus erythematosus early is crucial for managing the skin and potential systemic symptoms.

Methotrexate treats various disorders by inhibiting DNA synthesis, but careful monitoring is needed to avoid toxicity and manage side effects.

Microneedles improve drug delivery in various body parts, are safe and painless, and show promise in cosmetology, vaccination, insulin delivery, and other medical applications.

Exosomes could potentially enhance tissue repair and regeneration with lower rejection risk and easier production than live cell therapies.

Stress can cause hair loss by negatively affecting hair follicles and this effect might be reversed with specific treatments.

Some drugs can cause skin, nail, and hair problems, which are important for healthcare professionals to recognize and report.

Aminopterin strongly suppresses epithelial tissues and can treat certain skin conditions but has significant side effects.

Finasteride helps regrow hair and shrink prostate by reducing DHT, with some sexual side effects.

The document concludes that diagnosing and treating Human African Trypanosomiasis is challenging, but new treatments like fexinidazole are promising.

PDRN helps repair tissue and improve wound healing with a high safety profile.

New treatments for male hypogonadism are effective and should be personalized.

The study identified and characterized new keratin genes linked to hair follicles and epithelial tissues.

New LPA receptors (LPA4, LPA5, LPA6) have diverse roles in the body.

Some plant-based treatments can help with benign prostatic hyperplasia symptoms, but more research is needed to confirm their safety and effectiveness.

The document concludes that early recognition and treatment of primary cicatricial alopecia is crucial to prevent permanent hair loss.

Certain growth factors can promote hair growth in mice by activating hair growth-related proteins.

Using CRISPR for gene editing in the body is promising but needs better delivery methods to be more efficient and specific.