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Overactive Wnt signaling in mouse skin stem cells causes acne-like cysts and shrinking oil glands, which some treatments can partially fix.

Mechanical forces are crucial for shaping cells and forming tissues during development.

Epidermal stem cells have various roles in skin beyond just maintenance, including forming specialized structures and aiding in skin repair and regeneration.

A zinc-deficient diet stunted growth and affected organs in mice, with C57BL/6J mice showing more severe symptoms.

Intestinal intraepithelial lymphocytes are crucial for gut immunity and maintaining the mucosal barrier.

Mannan oligosaccharides improve raccoon dogs' fur quality and overall health.

Nrf-2-modified stem cells from hair follicles significantly improve ulcerative colitis in rats.

Minoxidil's absorption is too variable for it to be a reliable reference drug.

T cells and bacteria in the gut and skin help maintain health and protect against disease.

Early diagnosis and a strict gluten-free diet are crucial for children with celiac disease to improve symptoms.

The document concludes that accurate diagnosis of male and female gonadal disorders is crucial for effective treatment and better patient outcomes.

High levels of the protein Flightless I worsen ulcerative colitis symptoms in mice.

A Laotian man with unusual skin changes and multiple growths in his gut was diagnosed with Cronkhite-Canada Syndrome and improved with nutritional and immune-based treatments.

Cronkhite-Canada syndrome is rare, has a poor prognosis, and requires early diagnosis and ongoing treatment.

Epigenetic changes control how adult stem cells work and can lead to diseases like cancer if they go wrong.

Human alpha defensin 5 helps heal wounds, reduce bacteria, and grow hair on burned skin.

Targeting NETs may help reduce fibrosis in Crohn's disease.

A mother and son both had ulcerative colitis and alopecia, suggesting a genetic link in autoimmune disorders and successful treatment with cyclosporine.

Certain immune cells worsen post-surgery gut paralysis by activating a specific immune response.

The Wnt/β-catenin pathway is important for body functions and diseases, and targeting it may treat conditions like cancer, but with safety challenges.

Understanding how epigenetic regulation affects stem cells is key to cancer insights and new treatments.

An 8-year-old Saudi boy was diagnosed with a rare genetic disorder causing hair loss, skin issues, and light sensitivity.

Edible seeds from the Cucurbitaceae family like pumpkin and watermelon seeds are nutritious and may have health benefits, but eating too much can cause side effects.

Dermal papilla cells are key for hair growth and color, influencing hair type and size, and their interaction with stem cells could help treat hair loss and color disorders.

Mutations in the vitamin D receptor cause hereditary vitamin D-resistant rickets, leading to poor bone health and requiring high calcium doses for treatment.

Runx1 affects hair growth, cancer development, and autoimmune diseases in epithelial tissues.

A gluten-free diet stopped a child's hair-eating behavior and suggested she had celiac disease.

Proper niche formation in Drosophila requires Slit-Robo signaling for cell migration.

Organoid technology is advancing and entering commercial use, with applications in disease modeling, drug development, and personalized medicine.