research The Microanatomy of Human Skin in Aging
Aging skin shows thinner layers, fewer hair follicles, and new biomarkers like increased space between cells and smaller sebaceous glands.
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research Resident Macrophages of the Lung and Liver: The Guardians of Our Tissues
Lung and liver macrophages protect our tissues and their dysfunction can cause various diseases.
research Localized Alopecic Myxedema of the Scalp
A person with thyroid problems had rare, swollen, bald spots on their scalp caused by a condition usually found on the shins.
research Anti-Ku Antibodies: Much More Than Scleromyositis
Patients with Systemic Sclerosis have much higher levels of GDF-15, which could help predict organ involvement and guide treatment.
research Undifferentiated Connective Tissue Disease Presenting with Vascular Pattern of Renal Amyloidosis and Carpal Tunnel Syndrome: A Case Report
A woman with undifferentiated connective tissue disease was diagnosed with renal amyloidosis and carpal tunnel syndrome.
research Generalized Granuloma Annulare: A Therapeutic Challenge. Our Experience in 12 Patients
Treating generalized granuloma annulare is difficult, with PUVA being the most effective option, but relapses are common.
research Alopecia Universalis in a Dog with Testicular Neoplasia
A combination of ciclosporin and ketoconazole can effectively treat severe hair loss in dogs.
research Effects of 5-Alpha Reductase Inhibitors on Lung Function: A Reason for Discontinuation During COVID-19 Pandemic?
5-alpha reductase inhibitors might worsen lung recovery in COVID-19 patients, suggesting a pause in their use.
research Finasteride-Related Leydig Cell Tumor: Report of a Case and Literature Review
Finasteride use may be linked to rare testicular tumor, but more research needed.
research Physiology of Testicular Function
The testes produce sperm and hormones essential for male development.
research Late Onset Systemic Lupus Erythematosus: Clinical and Autoantibody Profile Compared with Young Onset Systemic Lupus Erythematosus
Late onset SLE has different symptoms and antibody profiles compared to young onset SLE.
research Telocytes Are a Critical Source of Wnts Essential for Hair Follicle Regeneration
Telocytes, cells with long extensions, are vital for hair growth because they produce Wnt signals, which are necessary for hair follicle regeneration.
research Accelerated UIP: A Special Challenge
Diagnosing and treating rapidly worsening lung disease is difficult and requires better guidelines and understanding.
research Gefitinib: An Adverse Effects Profile
Gefitinib can cause skin problems, diarrhea, and nausea, but rarely causes severe lung disease or hair loss.
research CD123 Immunohistochemistry for Plasmacytoid Dendritic Cells Is Useful in the Diagnosis of Scarring Alopecia
Using CD123 to detect certain immune cells helps diagnose a type of hair loss condition.
research Anti-Androgenic Therapy with Finasteride Improves Cardiac Function, Attenuates Remodeling, and Reverts Pathologic Gene Expression After Myocardial Infarction in Mice
Finasteride improves heart function and repairs damage after heart attack in mice.
research Systemic Autoimmune Diseases: Insights and Advances
The document concludes that systemic autoimmune diseases are complex, incurable, and require ongoing treatment and research.
research Physiological and Histological Study of the Effect of Finasteride Drug (Prostacare) on the Fertility of Albino Male Rats
Finasteride significantly reduces fertility in male rats.
research An Autopsy Case of Unicentric Castleman's Disease Associated with Bronchiolitis Obliterans
A woman with Castleman's disease died from respiratory failure due to bronchiolitis obliterans.
research Clinical Guidance on the Monitoring and Management of Trastuzumab Deruxtecan (T-DXd)-Related Adverse Events: Insights from an Asia-Pacific Multidisciplinary Panel
Proactive monitoring and management are essential to maximize the benefits of Trastuzumab Deruxtecan while minimizing serious side effects.
research Comparison of Allogeneic Stem Cell Transplant Conditioning Regimens in AML, MDS, and CLL
Busulfan/cyclophosphamide and total bone irradiation are equally effective for AML transplants.
research Epigenetic Mechanism of Gtl2-miRNAs Causes the Primitive Sheep Characteristics Found in Purebred Merino Sheep
A special gene region controls the re-emergence of a primitive wool type in Merino sheep, improving their wool yield and adaptability.
research Hallmark Evidence of Lipopolysaccharide Tolerance in Obese Women with Polycystic Ovary Syndrome: LPS-Induced NFkB Suppression in Mononuclear Cells Linked to Hyperandrogenism
High levels of testosterone and anti-Müllerian hormone before pregnancy are linked to a higher risk of newborns needing intensive care.
research Status of Sex Reassignment Surgery for Gender Identity Disorder in Japan
In Japan, sex reassignment surgery for gender identity disorder faces challenges and needs better medical support and education.
research Pathobiology Questions Raised by Telogen Effluvium and Trichodynia in COVID-19 Patients
COVID-19 may cause hair loss and scalp pain due to inflammation and changes in hair follicle receptors, but these symptoms typically resolve in 2 to 4 months.
research Linking Allergy to Mercury to HLA and Burning Mouth Syndrome
Mercury allergy linked to specific genes may contribute to burning mouth syndrome, and silicon might play a role in maintaining healthy hair.
research Scalp Cooling in the Prevention of Anthracycline-Induced Alopecia
Scalp cooling prevented hair loss in half of the patients, despite significant side effects.
research P576 Kerion: A Nasty Scalp Infection
Kerion is a rare but serious scalp infection that needs proper treatment.
research Consideration When Interpreting Outpatient Data
Objective assessment is needed to accurately determine medication use and adherence.
research SFRP2/DPP4 and FMO1/LSP1 Define Major Fibroblast Populations in Human Skin
Two main types of fibroblasts with unique functions and additional subtypes were identified in human skin.