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Fadrozole and Finasteride change frog sex ratios and cause intersex animals with altered gene expressions.

5-alpha reductase deficiency leads to male sexual development issues and treatments like finasteride help with prostate enlargement and hair loss.

Finasteride affects prostate development differently in male and female Mongolian gerbils.

Younger transgender women have surgery earlier, are mostly attracted to men, and show more preoperative depression that improves after surgery compared to older transgender women.

Finasteride negatively affects fish reproduction and gonadal development.

Cyproterone acetate is effective for acne but less so for hirsutism and alopecia, with some side effects and quick menstrual cycle recovery after treatment.

Masculine facial features may not reliably indicate heritable health, and more research is needed.

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

In Japan, sex reassignment surgery for gender identity disorder faces challenges and needs better medical support and education.

Genetic counselors should be culturally skilled and aware of transgender patients' unique health risks and needs.

Pediatric dermatologists need to understand the unique skin health needs of LGBTQIA youth to provide better care.

The guidelines recommend informed consent for gender-affirming treatments and stress the importance of personalized, culturally sensitive care for transgender individuals.

The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.

The document concludes that non-binary individuals need compassionate support and recognition in healthcare, without being pathologized.

Human skin makes sexual hormones that affect hair growth, skin health, and healing; too much can cause acne and hair loss, while treatments can manage these conditions.

Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.

Congenital Adrenal Hyperplasia is a genetic disorder with two forms, causing symptoms like early puberty and severe acne, but can be identified through screening and treated with glucocorticoids.

Androgens, like testosterone, are crucial for early testicular descent in rats.

Surgeons must understand the full care process for gender confirmation surgery to help transgender individuals effectively.

5α-reductase is essential for male sexual development and its inhibitors have potential in treating various conditions related to hormone action.

The document concludes that proper diagnosis and a multidisciplinary approach are crucial for managing Congenital Adrenal Hyperplasia effectively.

Antiandrogens affect androgen-dependent body functions and are used for various medical conditions, with some risks like fetus feminization, but new forms like 17α-propylmesterolone show promise for acne without systemic effects.

Amenorrhea is relatively rare and initial testing should check FSH, TSH, and prolactin levels.

The document explains how the male reproductive system works, its role in making testosterone, and how conditions like obesity can disrupt it, leading to low testosterone and fertility issues.

Men taking 5α-reductase inhibitors for enlarged prostate have a higher chance of experiencing reduced sexual desire and erectile dysfunction.

Women with excess body hair feel psychological distress influenced by societal beauty standards, but distress isn't directly linked to the amount of hair.

DHT, a testosterone byproduct, causes male pattern baldness.

Excessive hair growth in women often has no known cause and is not linked to race or other hormonal symptoms.

Understanding the fruiting patterns of Ficus trees can improve forest restoration by ensuring pollinators survive and biodiversity is supported.

The document concludes that identifying the cause of amenorrhea is crucial for proper treatment.