348 citations
,
July 2017 in “Skin appendage disorders” This review discusses the use of platelet-rich plasma in dermatology for various applications such as tissue regeneration and wound healing, but it reports no new clinical results and calls for clearer guidance on suitable treatments.
113 citations
,
July 2020 in “International Journal of Molecular Sciences” This review suggests that allogenic adipose stem cell and extracellular matrix transplants may be safe and effective for various medical conditions, based on available studies.
99 citations
,
August 2003 in “Fertility and Sterility” This paper discusses polycystic ovary syndrome with a focus on androgen excess as the primary symptom and notes that insulin resistance may contribute to it in many patients, but provides no new research findings.
90 citations
,
July 2014 in “Conservation Physiology” This study found that hair cortisol concentration in free-ranging brown bears is influenced by handling methods, body condition, and potentially both short- and long-term stressors.
78 citations
,
August 2017 in “Endocrine Reviews” This review discusses the free hormone hypothesis for measuring "free" testosterone and critiques its theoretical basis and clinical application, noting it lacks critical empirical testing and has inconsistent utility in assessing androgen status.
68 citations
,
February 2011 in “European Journal of Pharmaceutics and Biopharmaceutics” This study found that keratin films made from human hair can potentially substitute for human nail plates in drug permeability studies, but they show higher sensitivity to penetration enhancers compared to bovine hooves.
55 citations
,
September 2017 in “Expert Opinion on Drug Discovery” This review examines the main absorption sites and influencing factors for orally administered drugs, highlighting variables such as solubility and gastrointestinal conditions that affect drug absorption in the small intestine and the development of effective drug delivery systems.
42 citations
,
September 1985 in “British Journal of Dermatology” This study found that trichothiodystrophic hair shows reduced and disoriented protein deposition in follicles, with both the cuticle and cortex affected, providing localized structural insights into keratin abnormalities.
39 citations
,
June 2017 in “Scientific Reports” Different lab conditions and light treatment methods change how human skin cells respond to light therapy.
39 citations
,
January 2009 in “Journal of Ovarian Research” This study found moderate to poor agreement among observers assessing ultrasonographic features of polycystic ovaries, suggesting the need for standardized training modules to improve consistency.
37 citations
,
January 2009 in “Dermatology” This study reports that hair growth and shedding in healthy women show annual seasonal patterns, with the highest shedding in summer and a less pronounced peak in spring.
35 citations
,
January 2000 in “Dermatology” In this study, Norwegian men aged 20-50 who perceived themselves as having more hair loss reported greater dissatisfaction and concern about aging compared to those without hair loss.
28 citations
,
November 2009 in “Journal of Structural Biology” This study found that the molecular structure of hair is more sensitive to synchrotron X-ray radiation than its supramolecular architecture, indicating potential concerns for biological analyses using such radiation.
27 citations
,
September 2018 in “Skin appendage disorders” This review suggests that hair transplantation may be a viable treatment option for certain primary scarring alopecias, although findings should be interpreted cautiously due to possible publication bias favoring positive results.
27 citations
,
November 2015 in “American Journal of Primatology” This review discusses the use of stable isotope analysis in primate hair to study feeding behavior and reports no new results; the authors call for methodological refinement in field and lab procedures.
25 citations
,
February 2007 in “Forensic science international” This study found that different decontamination protocols caused varying levels of cuticle damage in hair, with aqueous buffer treatment resulting in the most substantial degradation.
21 citations
,
November 2011 in “Veterinary Pathology” This study evaluated skin and hair color variations in different mouse strains, highlighting the association between hair cycle stages and skin pigmentation to better understand these features and their implications.
20 citations
,
January 2015 in “Polish Journal of Pathology” Reflectance confocal microscopy is a useful, non-invasive tool for diagnosing some skin diseases, with potential for future improvements.
14 citations
,
August 2012 in “Clinics in Dermatology” This review discusses the pathogenesis, epidemiology, clinical features, histology, and treatment of frontal fibrosing alopecia and reports no new clinical results; the authors highlight its increasing incidence and challenging nature.
12 citations
,
November 2022 in “Toxics” This review describes how liver and kidney diseases and diabetes may affect ethyl glucuronide levels in hair, impacting forensic and clinical interpretations, but reports no new experimental results.
12 citations
,
January 2020 in “Analyst” This study found that untargeted hair metabolomics analysis detected significantly altered endogenous biomolecules, potentially serving as biomarkers for identifying oxidative cosmetic hair treatments like bleaching.
11 citations
,
April 2020 in “Animals” This study reported that relocation in police horses was associated with elevated hair cortisol concentrations, possibly suggesting altered welfare due to changed surroundings, and that seasonal variations affected both cortisol levels and hair growth.
10 citations
,
February 2016 in “The Journal for Nurse Practitioners” This article discusses the basic care and issues primary care providers should consider when treating transgender patients, but it reports no new clinical results.
8 citations
,
March 2023 in “Journal of Clinical Epidemiology” This updated guidance from the GRADE working group addresses issues with assessing inconsistency in treatment effect estimates and evaluating the credibility of effect modifiers in systematic reviews.
8 citations
,
April 2012 in “Korean journal of medicinal crop science/Han-gug yagyong jagmul hag-hoeji” This study found that the herbal product containing Rosa multiflora roots extract improved hair density and thickness and significantly promoted hair growth in both mice and human patients after 16 weeks of treatment.
7 citations
,
January 2019 in “Journal of Analytical Toxicology” This study found that hair samples from chronic tramadol and cannabis users showed positive drug presence for 3-4 months and 6-7 months, respectively, after discontinuation.
6 citations
,
March 2007 in “BioTechniques” This study observed that PCR-based genotyping for cre-loxP mice can lead to errors due to cre-mediated recombination in non-target tissues like tails, affecting the detection of lox alleles.
4 citations
,
December 2020 in “Journal of the American Academy of Dermatology” Pulling 2 or fewer hairs is normal for all hair types, including Afro- and Asian-textured hair.
4 citations
,
April 2020 in “Dermatology practical & conceptual” This review outlines the practical use of reflectance confocal microscopy in dermatology, detailing its applications and considerations for diagnosing various skin conditions, but reports no new findings.
3 citations
,
October 2015 in “Human Psychopharmacology-clinical and Experimental” In this study, finasteride was found not to be associated with changes in sleep spindle activity or morphology in men undergoing sleep studies.