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The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Men over 66 taking medication for prostate enlargement have a higher risk of depression and self-harm, especially in the first 18 months of treatment.

Starting 5-alpha reductase inhibitors does not significantly increase the risk of rhabdomyolysis in older men, but is linked to a higher risk of muscle conditions.

Black ethnicity, prior PSA tests, enlarged prostate, and family history increase prostate cancer risk; Asian ethnicity, obesity, smoking, diabetes, and less sexual activity or no children decrease risk.

Rats had lasting erectile problems after stopping a certain medication.

Using finasteride or dutasteride may cause long-lasting erectile dysfunction.

The document concludes that there are various treatments for different types of alopecia, but more research is needed for evidence-based treatments.

Low testosterone does not prevent prostate cancer in men with type 1 diabetes.

The conclusion suggests that prostate cancer should be classified by castration status and that new therapies targeting androgen receptor signaling show promise.

Certain HSD3B1 gene types are linked to worse prostate cancer outcomes and affect treatment response and other health conditions.

Finasteride is popular for treating male hair loss but may increase the risk of serious prostate cancer and has other potential side effects.

New treatments for prostate cancer and BPH show promise, including novel compounds that target hormone synthesis and response.

Researchers found 63 genes linked to male-pattern baldness, which could help in understanding its biology and developing new treatments.

Antiandrogens have important biological effects, but more research is needed to understand them fully and compare their effectiveness and side effects to other treatments.

Pumpkin seeds may improve health due to their rich nutrients and potential to treat various conditions.

Pica disorder in central Iraq is mainly found in females and is linked to low iron levels; treatment with iron improves most patients.

Finasteride for hair loss increases risk of long-lasting sexual dysfunction.

The document concludes that hormonal biomarkers are key for diagnosing hyperandrogenemia in women and hypogonadism in men.

BRL 7660, once studied for male contraception, showed promise as an acne treatment but was not developed further due to competing drugs.

Higher testosterone levels can increase the risk of certain diseases like type 2 diabetes in women and prostate cancer in men, but can also protect against autoimmune diseases and hair loss. It also affects body fat and bone density.

Neem is highly beneficial for health and beauty with no major side effects.

New liposome treatment successfully delivers CRISPR to deactivate a key enzyme in androgen-related disorders.

Oral ivermectin effectively cured scabies with minimal side effects, and finasteride promoted hair growth in men with hair loss.

SHBG may be a useful early indicator and treatment target for PCOS.

The lecture concluded that drugs for human enhancement are here to stay and called for their responsible development and fair access.

Men taking dutasteride or finasteride have a slightly higher risk of developing type 2 diabetes.

Finasteride can treat prostatic haematuria, but its use is controversial.

Men's sensitivity to male hormones might affect how severe COVID-19 gets for them.

The study found that certain microRNAs are higher in the cells and lower in the fluid of women with a specific type of polycystic ovary syndrome, and one microRNA could potentially help diagnose the condition.

The drug enzalutamide may reduce the ability of the virus causing COVID-19 to enter lung cells.