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FOXN1 gene variants cause low T cells and immune issues from birth.

Androgens affect bone and fat cell development differently based on the cells' embryonic origin.

Tocilizumab treatment was associated with significant hair regrowth in one patient and temporary hair loss followed by regrowth in another.

AGA causes hair loss by shrinking hair follicles due to DHT binding, and can be treated with finasteride and minoxidil.

Stress-related substance P may lead to hair loss and negatively affect hair growth.

The conclusion is that Treg-targeted therapies have potential, but more knowledge of Treg biology is needed for effective treatments, including for cancer.

Acne is caused by genetics, diet, hormones, and bacteria, with treatments not yet curative.

Oestrogens help maintain healthy skin, heal wounds, and may protect against skin aging and cancer.

Pitx2 helps outer root sheath cells differentiate but can't start hair growth on its own.

Double-stranded RNA causes inflammation in hair follicle cells, which may help understand and treat alopecia areata.

TLR4 is important in aging-related diseases and could be a new treatment target.

Biologic treatments for Crohn's disease and ulcerative colitis can cause skin problems, and doctors should adjust treatment if these occur.

Sebaceous glands in our skin, developing during pregnancy and active in puberty, produce sebum for skin lubrication, temperature control, and fighting germs, also help in hormone regulation, and their dysfunction can cause conditions like acne and hair loss.

Excessive sun protection might cause frontal fibrosing alopecia by disrupting skin immune balance.

Some treatments for autoimmune hair loss work, but JAK inhibitors like tofacitinib are promising for regrowth.

A woman with alopecia regrew her hair after taking a higher dose of tocilizumab.

Stress stops hair growth in mice by causing early hair growth phase end and harmful inflammation through a specific nerve-related pathway.

Capsaicin, found in chili peppers, can slow down hair growth by affecting skin cells and hair follicles.

Probiotic bacteria improved skin and hair health in aged mice.

Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.

C60 fullerenes can alter protein function and may help develop new disease inhibitors.

Hormones and metabolism play a complex role in prostate enlargement, and more research is needed to improve diagnosis and treatment.

Growth factors are crucial for hair development and could help treat hair diseases.

TCDD speeds up skin barrier formation by increasing certain gene expressions.

Hidradenitis suppurativa is caused by genetic factors, inflammation, bacteria, hormones, and lifestyle factors like obesity and smoking.

Anti-acne medications may work by reducing the activity of a protein involved in acne development.

GLP-1 receptor agonists, like Dulaglutide, Liraglutide, and Semaglutide, have potential benefits beyond the pancreas, including neuroprotection, pain suppression, cardiovascular protection, obesity management, and cancer treatment, but there are concerns about pancreatitis and pancreatic cancer risks.

The conclusion is that individual differences in COVID-19 severity are influenced by factors like age, sex, race, and genetics, which are important for personalized medicine.

Hormones during pregnancy and lactation keep skin stem cells inactive, preventing hair growth.

Androgens may block hair growth signals, targeting this could treat hair loss.