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The document concludes that drug repurposing, which is reusing known medicines for new illnesses, can provide faster, cheaper treatment options for various serious diseases, including cancer, COVID-19, and rare diseases.

Formyl-peptide receptor agonists could be new anti-inflammatory drugs.

Androgen receptors are key for development and health, affecting conditions like prostate cancer and male pattern baldness.

TRPV3 could be a target for treating pain, skin disorders, and hair problems, but more research is needed to create effective drugs.

Changes to the Foxp3 protein affect how well regulatory T cells can control the immune system, which could help treat immune diseases and cancer.

Lysophosphatidic acid is important for skin health and disease, and could be a target for new skin disorder treatments.

Hormones during pregnancy and lactation keep skin stem cells inactive, preventing hair growth.

Male hormones worsen kidney transplant damage, but blocking them helps.

Hair can regrow in large wounds through a process similar to how hair forms in embryos, and understanding this could lead to new treatments for hair loss or scarring.

Gene network oscillations inside hair stem cells are key for hair growth regulation and could help treat hair loss.

TIP39 and PTH2R help control calcium levels and skin cell development.

Certain types of T cells are essential for healthy skin and play a role in skin diseases, but more research is needed to improve treatments.

The document concludes that the development of certain tumors is influenced by genetic background and that a specific gene modification can lead to tumor regression and reduced growth.

Botulinum toxin type A significantly reduces scalp psoriasis severity compared to placebo.

Gene therapy shows promise for healing chronic wounds but needs more research to overcome challenges.

Fibroblasts are crucial for tissue repair and inflammation, and understanding them can help treat fibrotic diseases.

Some growth factors, while important for normal body functions, can cause diseases when not regulated properly.

Mice with autoimmune hair loss showed signs of heart problems.

Apoptosis may contribute to hair loss in androgenetic alopecia.

Targeting colon cancer stem cells might lead to better treatment results.

Possible link between androgens and COVID-19 severity; more research needed.

People with hidradenitis suppurativa are more likely to have bipolar disorder than those with psoriasis or without skin conditions.

Stress increases a factor in mice that leads to hair loss, and blocking this factor may prevent it.

CD4+ skin cells may be precursors to basal cell carcinoma.

Postpartum depression is linked to changes in brain chemicals, inflammation, stress, and certain genes, and can potentially be identified by markers like specific steroids, serotonin levels, and vitamin D levels.

Dupilumab helped improve skin and prevent new lesions in a child with a rare immune disorder and severe eczema.

Mast cells and CD8 T cells interact closely in skin diseases, affecting each other's behavior and contributing to conditions like psoriasis and eczema.

A protein called ectodysplasin-A2 increases a hair growth inhibitor in balding cells, which could be a target for hair loss treatment.

The conclusion suggests that prostate cancer should be classified by castration status and that new therapies targeting androgen receptor signaling show promise.

Sex hormones may influence COVID-19 severity, with males at higher risk, and certain hormone therapies could potentially treat the virus.