56 citations,
June 2015 in “Nature Protocols” Two-photon microscopy helps observe hair follicle stem cell behaviors in mice.
43 citations,
July 2014 in “Experimental Dermatology” Hair follicles can help wounds heal faster and this knowledge could be used to treat chronic skin ulcers, with a potential use of a special stem cell hydrogel to enhance healing.
29 citations,
May 2020 in “npj Regenerative Medicine” Immune cells help regulate hair growth, and better understanding this can improve hair loss treatments.
13 citations,
December 2017 in “Stem cells” Low-dose radiation affects hair stem cell function and survival by changing their genetic material's structure.
4 citations,
December 2022 in “Advanced science” SCD1 is important for hair growth by keeping the connection in skin cells where hair stem cells live stable.
4 citations,
July 2022 in “Annals of translational medicine” Scientists created complete hair-like structures by growing mouse skin cells together in a special gel.
January 2020 in “Egyptian Journal of Dermatology and Venereology” People with alopecia have shorter hair follicles and more c-kit, a stem cell factor receptor, which could predict how the condition progresses.
January 2022 in “Stem cell biology and regenerative medicine” Lymphatic vessels help hair follicles regenerate by interacting with stem cells.
82 citations,
February 2017 in “Cold Spring Harbor Perspectives in Biology” The TGF-β family helps control how cells change and move, affecting skin, hair, and organ development.
May 2022 in “Research Square (Research Square)” Nestin marks cells that can become a specific type of skin cell in hair follicles of both developing and adult mice.
36 citations,
October 2015 in “Cell reports” Gab1 protein is crucial for hair growth and stem cell renewal, and Mapk signaling helps maintain these processes.
1 citations,
October 2022 in “Scientific reports” Nestin identifies specific progenitor cells in hair follicles that can become outer root sheath cells.
June 2021 in “bioRxiv (Cold Spring Harbor Laboratory)” KIF18B is important for correctly positioning cell division machinery in skin cells, affecting hair follicle development.
16 citations,
July 2016 in “Journal of Dermatological Science” Regenerated hairs can regain their color if the wound occurs during a certain stage of hair growth, and this process is helped by specific skin cells and proteins.
120 citations,
August 2008 in “The journal of investigative dermatology/Journal of investigative dermatology” Cytokeratin 19 and cytokeratin 15 are key markers for monitoring the quality and self-renewing potential of engineered skin.
36 citations,
January 2004 in “European journal of cell biology” Without keratin 10, there's more growth and development of oil-producing skin cells.
5 citations,
September 2010 in “Cancer Prevention Research” The research suggests new treatments for skin cancer could target specific cell growth pathways.
2 citations,
September 2022 in “Frontiers in Immunology” T-regulatory cells are important for skin health and can affect hair growth and reduce skin inflammation.
1 citations,
February 2016 in “Cell Transplantation” Hair follicles have a more inactive cell cycle than other skin cells, which may help develop targeted therapies for skin diseases and cancer.
359 citations,
January 2015 in “Cold Spring Harbor Perspectives in Medicine” Hair growth phase and certain genes can speed up wound healing, while an inflammatory mediator can slow down new hair growth after a wound. Understanding these factors can improve tissue regeneration during wound healing.
253 citations,
April 2008 in “Current opinion in cell biology” Notch signalling helps skin cells differentiate and prevents tumors.
170 citations,
July 2012 in “Journal of Investigative Dermatology” Wnt ligands are crucial for hair growth and repair.
126 citations,
April 2006 in “International Journal of Dermatology” The conclusion is that FFA and LPP have similar scalp biopsy features, making them hard to distinguish histologically, and FFA may be a specific kind of scarring hair loss.
97 citations,
September 2016 in “Reviews in Endocrine and Metabolic Disorders” The sebaceous gland has more roles than just producing sebum and contributing to acne, and new research could lead to better skin disease treatments.
60 citations,
April 2012 in “Physiology” The document concludes that understanding hair and feather regeneration can help develop new regenerative medicine strategies.
57 citations,
March 2013 in “Journal of Dermatological Science” Improving the environment and cell interactions is key for creating human hair in the lab.
47 citations,
January 2015 in “Dermatology” The best way to treat acne is to prevent healthy skin glands from turning into acne lesions by controlling the triggers early on.
38 citations,
September 2014 in “Cell and Tissue Research” The hair follicle infundibulum plays a key role in skin health and disease, and understanding it better could lead to new skin disease treatments.
36 citations,
July 2014 in “Experimental Dermatology” Skin and hair can regenerate after injury due to changes in gene activity, with potential links to how cancer spreads. Future research should focus on how new hair follicles form and the processes that trigger their creation.
30 citations,
November 2020 in “Journal of Advanced Research” Conditioned medium from keratinocytes can improve hair growth potential in cultured dermal papilla cells.