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The human skin's outer layer has more variety in cell types and development paths than previously thought.

Fluocinolone acetonide slows down hair follicle stem cells but speeds up skin cell growth in mice.

Aging changes skin cells, leading to different DNA methylation and gene activity, affecting cell metabolism and aging signs.

Conditioned medium from keratinocytes can improve hair growth potential in cultured dermal papilla cells.

Skin stem cells are maintained by signals from nearby cells and vary in their ability to renew and mature.

Hair follicles have a more inactive cell cycle than other skin cells, which may help develop targeted therapies for skin diseases and cancer.

Claudin-1 is important for the barrier function and growth of hair.

Minoxidil slows down keratinocyte growth without being toxic.

Certain sex hormones and antiandrogens can either slow down or speed up the growth of human hair follicle cells depending on their concentration.

Hair follicle cells resist turning into skin cells.

Normal skin cell renewal doesn't need RAR signaling, but vitamin A-related skin thickening does.

Activin helps skin growth and healing mainly through stromal cells and affects keratinocytes based on its amount.

Minoxidil affects cell growth in two ways: low doses increase growth, while high doses slow it down and can be toxic.

A two-step method was created in 2015 to make more cells that help with hair growth, but they need to be combined with other cells for 4 days to actually form new hair.

Certain cells around hair follicles help improve skin regeneration for potential use in skin grafts.

Skin aging is due to impaired stem cell mobilization or fewer responsive stem cells.

Cytokeratin 19 and cytokeratin 15 are key markers for monitoring the quality and self-renewing potential of engineered skin.

Keratin 15 is not a reliable sole marker for identifying epidermal stem cells because it's found in various cell types.

Adding hyaluronic acid helps create larger artificial hair follicles in the lab.

Putting α-methylspermidine on mouse skin can start hair growth.

Chronic inflammatory skin diseases are caused by disrupted interactions between skin cells and immune cells.

Loss of keratin K2 causes skin problems and inflammation.

Retinoic acid-binding proteins in skin are regulated by β-catenin and Notch signalling.

Plet-1 protein helps hair follicle cells move and stick to tissues.

Activating Nrf2 in skin cells speeds up wound healing by increasing the growth of certain stem cells.

The research confirms that Hidradenitis Suppurativa is characterized by increased inflammation, disrupted skin cell organization, and abnormal metabolic processes.

Disrupted sleep patterns can harm skin and hair cell renewal, but melatonin might help.

Follistatin helps hair growth and cycling, while activin prevents it.

The review found that different stem cell types in the skin are crucial for repair and could help treat skin diseases and cancer.

Embryonic and adult stem cells are valuable for improving skin grafts and cell therapy.