11 citations,
February 1982 in “Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis” A new method can detect mutations in mice by observing changes in hair follicle cells.
53 citations,
October 1998 in “The journal of investigative dermatology/Journal of investigative dermatology” Topical calcitriol-analogs can reduce hair loss caused by chemotherapy.
5 citations,
February 2022 in “Stem cell reports” Thymic stromal lymphopoietin (TSLP) promotes hair growth, especially after skin injury.
[object Object] January 2022 in “Clinical Cases in Dermatology” A condition called Central Centrifugal Cicatricial Alopecia causes hair loss and scalp burning in middle-aged African women, and it's treated with various medications, hair transplants, and non-drug methods like wigs.
34 citations,
December 2011 in “The Journal of Dermatology” A unique type of lupus panniculitis causes reversible hair loss on the scalp in East Asians.
33 citations,
October 2013 in “PloS one” Human sweat glands have a type of stem cell that can grow well and turn into different cell types.
13 citations,
April 2019 in “iScience” EGFR helps control how hair grows and forms without needing p53 protein.
11 citations,
January 2019 in “International Journal of Trichology” Mesotherapy is not significantly better than minoxidil for treating male hair loss.
7 citations,
February 2023 in “Inflammation and Regeneration” The protein interleukin-1 alpha helps regenerate hair follicles and increase stem cell growth in mice.
6 citations,
April 2022 in “Journal of diabetes research” Type 2 diabetes slows down skin and hair renewal by blocking important stem cell activation in mice.
April 2024 in “Histochemistry and cell biology” N-acetylcysteine may prevent hair loss caused by chemotherapy.
April 2012 in “Cancer research” Blocking mTORC1 may help prevent skin cancer by stopping the growth of certain skin stem cells.
January 2022 in “JAAD case reports” Granulomatous alopecia areata is a rare but real form of hair loss.
January 2022 in “Indian Journal of Dermatology” 221 citations,
July 2012 in “Proceedings of the National Academy of Sciences of the United States of America” BMAL1 controls skin cell growth and UV damage risk, peaking at night.
215 citations,
November 2000 in “Journal of Investigative Dermatology” The system allows precise control of gene expression in mouse skin, useful for studying skin biology.
129 citations,
July 2019 in “Stem Cell Research & Therapy” Epidermal stem cells help heal severe skin wounds and have potential for medical treatments.
105 citations,
October 2018 in “Nature” A small group of slow-growing cells causes basal cell carcinoma to return after treatment.
90 citations,
April 2013 in “Dermatology online journal” Different treatments for Hidradenitis suppurativa range from antibiotics and hormonal therapies to surgery, depending on severity.
86 citations,
May 2002 in “Journal of Investigative Dermatology” A new keratin, hK6irs1, is found in all layers of the hair follicle's inner root sheath.
72 citations,
November 2017 in “Journal of developmental biology” The Hedgehog signaling pathway is important for skin and hair growth and can lead to cancer if it doesn't work right.
35 citations,
August 2009 in “Journal of the American Academy of Dermatology” Melanocytes might be targeted by the immune system in people with alopecia areata, but more research is needed.
34 citations,
January 2013 in “Frontiers in genetics” Stem cells can help other stem cells by producing supportive factors.
33 citations,
July 2007 in “Journal of cell science” Miz1 is essential for proper hair structure and growth.
17 citations,
January 2007 in “Annals of Medicine” Cutaneous gene therapy could become a viable treatment for skin and hair disorders with improved vector development and gene expression control.
16 citations,
May 2015 in “Tissue Engineering Part C-methods” A two-step method was created in 2015 to make more cells that help with hair growth, but they need to be combined with other cells for 4 days to actually form new hair.
[object Object] 13 citations,
April 2010 in “Journal of dermatological science” Chemotherapy-induced hair loss is partly due to decreased laminin-511 and increased laminin-332.
10 citations,
August 2021 in “EMBO Reports” The Bcl-2 protein is important for keeping hair follicle stem cells working and preventing hair loss.
9 citations,
March 2015 in “The journal of investigative dermatology/Journal of investigative dermatology” The symposium concluded that understanding the molecular mechanisms of skin aging could lead to better clinical practices and treatments.
8 citations,
October 2020 in “Stem cell research & therapy” DNMT1 helps turn hair follicle stem cells into fat cells by blocking a specific microRNA.