March 2002 in “Clin-Alert” In 2002, various drugs caused serious side effects, including vitamin B12 deficiency, heart issues, blindness, hypersexuality, allergic reactions, blood clotting problems, pupil dilation, capillary leak syndrome, muscle breakdown, hepatitis, skin reactions, and lupus.
13 citations
,
January 1999 in “Postgraduate Medicine” New drugs for rheumatoid arthritis show improvement but have side effects and are not a cure.
6 citations
,
December 2022 in “Journal of autoimmunity” JAK inhibitors like tofacitinib may effectively treat Alopecia Areata.
1 citations
,
June 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” Fetal skin has unique immune cells different from adult skin.
224 citations
,
March 2006 in “Seminars in Cutaneous Medicine and Surgery” The document concludes that understanding hair follicle biology can lead to better hair loss treatments.
77 citations
,
March 2001 in “Clinics in Dermatology” Androgenetic alopecia involves genetics, hormones, and can be treated with medications or surgery.
64 citations
,
August 2016 in “Journal of Immunology” Blocking the CXCR3 receptor reduces T cell accumulation in the skin and prevents hair loss in mice.
46 citations
,
September 2011 in “Journal of Endocrinology” Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.
38 citations
,
June 2019 in “International Journal of Women's Dermatology” The document concluded that more research is needed to find the best treatment for Frontal fibrosing alopecia.
37 citations
,
August 2019 in “Journal of The American Academy of Dermatology” Some treatments like intralesional steroids and 5α-reductase inhibitors are effective for frontal fibrosing alopecia, but more research is needed.
27 citations
,
July 2013 in “The journal of investigative dermatology/Journal of investigative dermatology” Somatostatin may help protect hair follicles from immune attacks.
23 citations
,
October 2018 in “Australasian Journal of Dermatology” The current understanding of frontal fibrosing alopecia involves immune, genetic, hormonal factors, and possibly environmental triggers, but more research is needed for effective treatments.
23 citations
,
October 2018 in “Expert Opinion on Drug Safety” Consider benefits and risks of new alopecia treatments for safety.
18 citations
,
January 2022 in “Anais Brasileiros de Dermatologia” COVID-19 can cause various skin issues, like rashes and lesions, which are more common in younger patients and can be linked to more severe complications.
11 citations
,
October 2021 in “Stem Cell Research & Therapy” Hair follicle stem cells reduced hair loss and inflammation in mice with a condition similar to human alopecia.
10 citations
,
August 2019 in “International Journal of Cosmetic Science” Some plant-based chemicals may help with hair growth, but more research is needed to confirm their effectiveness.
9 citations
,
March 2015 in “Journal of Microbiology and Biotechnology” Ultra-high molecular weight poly-γ-glutamic acid may help promote hair growth.
8 citations
,
February 2017 in “Experimental dermatology” Hair follicles may help teach the immune system to tolerate new self-antigens, but this can sometimes cause hair loss.
4 citations
,
June 2013 in “The Journal of Rheumatology” The document concludes that various findings in rheumatology offer insights into disease severity, treatment responses, and potential risks in medication, with some limitations due to unspecified participant numbers.
2 citations
,
July 2022 in “Frontiers in Medicine” The cause of Frontal fibrosing alopecia, a type of hair loss, is complex, likely involving immune responses and genetics, but is not fully understood.
1 citations
,
January 2010 in “Elsevier eBooks” Any drug can cause skin reactions, but antibiotics, NSAIDs, and psychotropic drugs are more common, with some reactions being life-threatening.
A girl with Crohn's disease developed hair loss due to her increased medication, a rare side effect seen in some children.
April 2021 in “Sohag Medical Journal” Alopecia areata is an autoimmune condition causing hair loss, linked to genetic factors and immune system issues, with no cure yet.
May 2015 in “Journal of The American Academy of Dermatology” Young men taking finasteride for hair loss have a higher risk of sexual dysfunction.
May 2015 in “Journal of The American Academy of Dermatology” Finasteride for hair loss increases risk of sexual dysfunction in young men.
8 citations
,
October 2022 in “International Journal of Molecular Sciences” Self-amplifying RNA could be a better option for protein replacement therapy with lower doses and lasting effects, but delivering it into cells is still challenging.
3 citations
,
March 2021 in “Journal of The American Academy of Dermatology” The document suggests that more research is needed to confirm if baldness can indicate a higher risk of severe COVID-19 in men.
25 citations
,
December 2018 in “Human Molecular Genetics” The document concludes that certain mutations may contribute to the inflammation in hidradenitis suppurativa and suggests that targeting TNFα could be a treatment strategy.
4 citations
,
June 2022 in “BioMed Research International” Using mesenchymal stem cells or their exosomes is safe for COVID-19 patients and helps improve lung healing and oxygen levels.
102 citations
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July 2020 in “International journal of molecular sciences” Hormones like testosterone and estrogen significantly affect hair growth and structure.