April 2024 in “Molecules/Molecules online/Molecules annual” Paris polyphylla saponins may effectively treat acne due to their antibacterial and anti-inflammatory properties.
December 2023 in “Animals” The study mapped yak skin cells to understand hair growth better.
1 citations,
November 2011 in “British journal of pharmacology” Enzymes are classified into six types and are essential for many biological processes, with only a few targeted by drugs.
36 citations,
December 2002 in “Experimental dermatology” Barley extract, specifically procyanidin B-3, can promote hair growth and counteract growth inhibition.
4 citations,
September 2011 in “Expert Review of Dermatology” Various treatments exist for alopecia areata, but none are completely satisfactory; choice depends on age, disease extent, and preference.
December 1997 in “Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE” Low-energy laser therapy can improve scalp alopecia treatment when combined with classical methods.
25 citations,
March 2012 in “Journal of oncology pharmacy practice” An 81-year-old man's white hair began to regain its original color while he was treated with lenalidomide, suggesting that graying hair might be reversible.
34 citations,
November 2010 in “Development” Activating Notch in adult skin causes T cells and neural crest cells to gather, leading to skin issues.
July 2023 in “Stem Cells Translational Medicine” Mesenchymal Stem/Stromal Cells (MSCs) help in wound healing and tissue regeneration, but can also contribute to tumor growth. They show promise in treating chronic wounds and certain burns, but their full healing mechanisms and potential challenges need further exploration.
May 1991 in “Current problems in dermatology” Skin issues can indicate immune system problems.
26 citations,
August 2008 in “Clinical endocrinology” The document concludes that more multidisciplinary research is needed to understand and treat PCOS, a condition that significantly affects women's health and quality of life.
51 citations,
October 2002 in “British Journal of Dermatology” Finasteride increases hair density in female androgenetic alopecia, but individual results may vary.
49 citations,
September 2012 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” The document concludes with guidance for doctors on diagnosing and treating hirsutism effectively and safely.
24 citations,
March 2022 in “Genome biology” scINSIGHT accurately identifies cell clusters and gene patterns in complex data.
4 citations,
October 2021 in “Journal of Cellular and Molecular Medicine” White blood cells and their traps can slow down the process of new hair growth after a wound.
March 2024 in “International journal of molecular sciences” Mitochondrial dysfunction is linked to various skin conditions and could be a target for treatments.
January 2012 in “Methods in pharmacology and toxicology” TRPV3 could be a target for treating pain, skin disorders, and hair problems, but more research is needed to create effective drugs.
54 citations,
December 2011 in “American Journal Of Pathology” A Gsdma3 mutation causes hair loss due to stem cell damage from skin inflammation.
89 citations,
May 1999 in “Allergy” The yeast Pityrosporum ovale can cause skin allergies and infections, and antifungal treatments like ketoconazole are effective against it.
96 citations,
December 2018 in “Immunity” Targeting TGFβ can improve skin immunity in older people.
36 citations,
March 2002 in “Journal of Biological Chemistry” Food deprivation increases MST enzyme in the brain, possibly affecting energy balance.
32 citations,
January 2000 in “Skin pharmacology and physiology” Certain substances that block a specific protein help promote hair growth.
11 citations,
August 2023 in “Burns” Nerve growth factor helps improve healing time and scar quality in burn wounds.
60 citations,
September 2013 in “Alimentary Pharmacology & Therapeutics” Immunosuppressive and anti-TNF therapies in IBD patients can increase the risk of skin cancer and cause various skin issues.
40 citations,
July 2015 in “Kidney International” IL-3 worsens lupus nephritis and blocking it improves kidney health.
19 citations,
December 2015 in “Journal of Investigative Dermatology” The protein p53 directly reduces the production of Keratin 17, a skin and hair protein, in rats with radiation dermatitis.
51 citations,
August 2013 in “The Journal of experimental medicine/The journal of experimental medicine” Loss of a specific protein in skin cells causes symptoms similar to psoriasis.
47 citations,
February 2021 in “Pharmacological research” Exosomes can improve skin health and offer new treatments for skin repair and rejuvenation.
58 citations,
October 2016 in “Journal of Investigative Dermatology” Activating Nrf2 protects human hair follicles from oxidative stress and helps prevent hair growth inhibition.
76 citations,
February 2021 in “International Journal of Molecular Sciences” Mesenchymal stem cells show potential for skin healing and anti-aging, but more research is needed for safe use, especially regarding stem cells from induced pluripotent sources.