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Calreticulin has roles in healing, immune response, and disease beyond its known functions in the endoplasmic reticulum.

The Rotterdam Study found risk factors for elderly diseases, links between lifestyle and genetics with health conditions, and aimed to explore new areas like DNA methylation and sensory input effects on brain function.

The skin has a complex immune system that is essential for protection and healing, requiring more research for better wound treatment.

Chemotherapy can cause various skin reactions, with hair loss being the most common, and proper diagnosis and treatment of these reactions are important.

The guidelines suggest a detailed approach to diagnosing and treating lupus, with a focus on regular check-ups, personalized medicine, and a range of drug options for different cases.

Targeted cancer therapies often cause serious skin problems that need careful management.

Alopecia areata is an autoimmune condition causing hair loss due to the immune system attacking hair follicles, often influenced by genetics and stress.

Current treatments for alopecia show no significant long-term benefits.

RNAi-based biopesticides could be safe and effective for pest control with careful development and risk assessment.

Periodontal ligament stem cells show promise for regrowing tissues but require more research for safe, effective use.

Exosomes could potentially enhance tissue repair and regeneration with lower rejection risk and easier production than live cell therapies.

Low doses of some substances can be beneficial, while high doses can be harmful or toxic.

Janus kinase inhibitors are promising treatments for autoimmune skin diseases like eczema and psoriasis.

Estrogens help reduce skin aging, and SERMs might offer similar benefits without the risks of hormone therapy.

Hair follicles are hormone-sensitive and involved in growth and other functions, with potential for new treatments, but more research is needed.

Prolactin affects hair growth and skin conditions, and could be a target for new skin disease treatments.

There are many treatments for permanent hair loss disorders, but their effectiveness varies and there's no clear best option.

No treatment fully prevents hair loss from chemotherapy yet.

Lichen planopilaris is a chronic, scarring hair loss condition with no definitive cure, requiring accurate diagnosis and treatment to manage symptoms.

Skin changes can help diagnose and manage endocrine disorders like thyroid problems, diabetes, and adrenal gland conditions.

The Foxn1 gene mutation causes hairlessness and immune system issues, and understanding it could lead to hair growth disorder treatments.

Keratin 15 is not a reliable sole marker for identifying epidermal stem cells because it's found in various cell types.

Certain types of T cells are essential for healthy skin and play a role in skin diseases, but more research is needed to improve treatments.

Environmental factors, hormones, nutrition, and stress all significantly affect skin health and aging.

Oestrogens help maintain healthy skin, heal wounds, and may protect against skin aging and cancer.

Advanced nanocarrier and microneedle drug delivery methods are more effective, safer, and less invasive for treating skin diseases.

Tissue-resident memory T cells can protect against infections and cancer but may also contribute to autoimmune diseases.

Stress can worsen skin conditions by affecting hormone levels and immune response.

Toll-like receptors are important for wound healing, but can slow it down in diabetic wounds.

Hair usually grows back 1-3 months after treatment for anagen effluvium, and children with Loose Anagen Hair Syndrome often improve by adolescence.