research Skipping of Exons by Premature Termination of Transcription and Alternative Splicing Within Intron-5 of the Sheep SCF Gene: A Novel Splice Variant
A new mRNA variant of the SCF gene in sheep skin produces a shorter, different protein.
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research Microneedling Dilates the Follicular Infundibulum and Increases Transfollicular Absorption of Liposomal Sepia Melanin
Microneedling helps increase the absorption of a melanin product into hair follicles, which may improve laser hair removal effectiveness.
research Vitamin D and the Skin
research Mesenchymal Stem Cell-Derived Exosomes for Organ Development and Cell-Free Therapy
MSC-Exos can aid organ development and offer therapeutic benefits for various conditions.
research The Effect of Mesenchymal Stem Cells and Chitosan Gel on Full Thickness Skin Wound Healing in Albino Rats: Histological, Immunohistochemical and Fluorescent Study
Mesenchymal stem cells, especially injected into the skin, heal wounds faster and better than chitosan gel or other treatments.
research MTOR Signaling in Hair Follicle and Hair Diseases: Recent Progress
The mTOR signaling pathway is crucial for hair health and targeting it may lead to new hair loss treatments.
research Role of 5α-Reductase in Health and Disease
5α-reductase is essential for male sexual development and its inhibitors have potential in treating various conditions related to hormone action.
research Advances in Platelet Rich Plasma-Derived Extracellular Vesicles for Regenerative Medicine: A Systematic-Narrative Review
Platelet Rich Plasma-Derived Extracellular Vesicles show promise for healing and regeneration but need standardized methods for consistent results.
research Epidermolysis Bullosa Simplex: A Paradigm for Disorders of Tissue Fragility
Epidermolysis bullosa simplex causes easily blistered skin due to faulty skin cell proteins, leading to new treatment ideas.
research Hairy Tale of Signaling in Hair Follicle Development and Cycling
Hair growth and development are controlled by specific signaling pathways.
research Spatial And Temporal Control Of Laminin-511 And -332 Expressions During Catagen
Laminin-511 may help promote hair growth, while laminin-332 does not affect hair loss.
research Enzymes
Enzymes play crucial roles in metabolism, health, and disease management.
research Topobiology of Human Pigmentation: P-Cadherin Selectively Stimulates Hair Follicle Melanogenesis
P-cadherin is crucial for hair follicle pigmentation but not skin pigmentation.
research Sic Transit Gloria: Farewell to the Epidermal Transit Amplifying Cell?
New research suggests that skin cell renewal may not require a special type of cell previously thought to be essential.
research Advances in Male Hormone Substitution Therapy
New treatments for low male hormones improved sexual function and mood but had unclear risks, especially for older men.
research Primary Generalized Glucocorticoid Resistance And Hypersensitivity
The conclusion is that genetic changes in the glucocorticoid receptor can lead to conditions affecting stress response, immunity, and metabolism, requiring personalized treatment.
research A Bald Statement: Current Approaches to Manipulate Miniaturization Focus Only on Promoting Hair Growth
The conclusion is that future hair loss treatments should target the root causes of hair thinning, not just promote hair growth.
research Mechanisms of Hepatocyte Attachment to Keratin Biomaterials
Human liver cells stick to hair protein materials mainly through the liver's asialoglycoprotein receptor.
research The Stem Cell Quiescence and Niche Signaling Is Disturbed in the Hair Follicle of the Hairpoor Mouse, an MUHH Model Mouse
Disrupted stem cell signals in hairpoor mice cause hair loss.
research Localization of Plasminogen Activator Inhibitor Type 2 in Hair and Nail: Implications for Terminal Differentiation
PAI-2 helps in the maturation and protection of hair and nail cells.
research Interferons in Dermatology
Interferons are effective for some skin conditions and cancers, but can have side effects and need more research for optimal use.
research Phospholipase A2 Is Required for PIN-FORMED Protein Trafficking to the Plasma Membrane in the Arabidopsis Root
Phospholipase A2 is necessary for the correct placement of PIN proteins in plant roots, affecting root growth.
research Whole-Genome Bisulfite Sequencing of Goat Skins Identifies Signatures Associated with Hair Cycling
DNA methylation changes are linked to hair growth cycles in goats.
research Ionizing Radiation Triggers Dedifferentiation of Outer Root Sheath Cells Into Stem Cell-Like Progenitors for Hair Follicle Regeneration
research Molecular Network of Smads and Id2 Genes in Hair Follicle Stem Cells Regulation
The BMP/Smads pathway and Id2 gene control hair follicle stem cells, affecting their rest and growth phases.
research Non-Rhizobial Nodule Endophytes Improve Nodulation, Change Root Exudation Pattern and Promote the Growth of Lentil for Prospective Application in Fallow Soil
Certain bacteria can boost lentil growth and improve soil used for farming.
research Two Mouse Mutations Mapped to Chromosome 11 with Differing Morphologies but Similar Progressive Inflammatory Alopecia
Two mouse mutations cause similar hair loss despite different skin changes.
research Biological Activities of 2,3,5,4′-Tetrahydroxystilbene-2-O-β-D-Glucoside in Antiaging and Antiaging-Related Disease Treatments
THSG from a Chinese plant helps with aging and related diseases.
research Regulation of the Wound Healing Response During Aging
Aging slows wound healing due to weaker cells and immune response.
research Recent Updates of the CRISPR/Cas9 Genome Editing System: Novel Approaches to Regulate Its Spatiotemporal Control by Genetic and Physicochemical Strategies
CRISPR/Cas9 has improved precision and control but still faces clinical challenges.