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This study identified ectomesenchyme as a major source of epidermal stem cells in mouse skin, with ectomesenchymal keratinocytes occupying a significant portion of the epidermal stem cell-enriched population.

This study found that epidermal-specific deletion of aPKCλ in mice disrupted hair follicle stem cell quiescence and regeneration, leading to abnormal hair cycling and skin changes.

This review examines the location and markers of hair follicle stem cells, finding that they are primarily located in the bulge region and can contribute to various skin structures, but challenges remain in distinguishing them from their progeny.

This study found that a combination of botanical extracts from jasmine, Longoza, peony, and lily significantly increased a6 and b4 integrin protein expression in human skin cells, suggesting complementary effects that could enhance skin quality.

In this study, gene inactivation in mouse hair follicle stem cells lacking ILK impaired wound healing by reducing their progeny’s contribution to the regenerating epidermis, but did not affect hair follicle regeneration.

This study found that keratinocyte stem/progenitor cell-conditioned medium significantly enhanced hair growth in mice and increased the proliferation of human hair follicle cells.

This study found that epidermal-specific deletion of integrin α3β1 significantly reduces papilloma formation in a skin carcinogenesis model by modulating HB stem cell behavior and CCN2 expression.

This review discusses the various evidence-based and potential applications of metformin in treating and preventing symptoms and complications associated with polycystic ovary syndrome but reports no new clinical results.

This review discusses the potential of small extracellular vesicles (sEVs) as next-generation therapeutics, noting their ability to overcome biological barriers and modulate cellular environments for various diseases.

In this systematic review, tSVF-based therapy demonstrated favorable outcomes for various pathologies, including aged skin and osteoarthritis, with low incidence of adverse events, while highlighting the need for further research into optimal protocols and mechanisms of action.

This study found that bulge-derived keratinocytes from human follicles were more resistant to differentiation compared to epidermal keratinocytes, possibly due to WIF-1 involvement.

This study reveals that CSPG4-positive basal cell keratinocytes show distinct global gene expression from CSPG4-negative cells, despite similar colony-forming efficiency.

This study observed that gerbils exhibit a different wound healing mechanism compared to mice, with lower TGF-B1 expression and distinct tissue responses, yet achieve similar healing outcomes.

This study found that ILK deficiency disrupts hair follicle development by impairing cell polarity and laminin-511 assembly, but these defects can be partially reversed with exogenous laminin-511.

This study found that the CD44(+) ALDH(+) population of neonatal human keratinocytes exhibited enhanced stem cell properties, including significantly increased long-term epidermal regeneration and multipotency, compared to unfractionated cells.

This study demonstrates that α-parvin is crucial for epidermal morphogenesis and hair follicle development by mediating integrin-dependent adhesion and actin organization in keratinocytes.

This study found that epidermal stem cells in nonglabrous skin are connected to the distal end of the arrector pili muscle, which may play a role in epidermal renewal and wound healing.

The document concludes that stem cells and their environments are crucial for skin and hair health and have potential for medical treatments.

This review examines integrins as pharmacological targets, discussing current integrin-based therapies and emphasizing the need to understand integrin mechanisms for successful drug development, without reporting new clinical results.

This study found that deleting the CD98hc protein in mouse skin impairs wound healing and homeostasis, resembling aging effects, due to disrupted integrin signaling pathways.

This study found that stress-induced inactivation of the enzyme Dicer in melanocytes can cause premature hair greying by preventing proper melanocyte placement and melanin transfer in mice, suggesting the Dicer-miR92b-ItgaV pathway as an important link between stress and grey hair.

This research explored the components of stem cell niches to better understand how epidermal stem cells are maintained, focusing on CD271+ cells in specific skin layers.

This study found that although progerin expression in mouse skin causes significant nuclear shape changes in keratinocytes, it does not result in alopecia or common skin abnormalities seen in human Hutchinson–Gilford progeria syndrome.

This study found that laminin-511 is crucial for hair morphogenesis in mice, as it influences primary cilia formation and dermal papilla maintenance through noggin and sonic hedgehog signaling.

Research on epidermal stem cells has advanced significantly, showing promise for improved clinical therapies.

This review discusses psychological impacts associated with facial acne, noting that high levels of anxiety and depression among these patients are not linked to oxidative stress, and reports no new clinical results.

This review discusses the use, efficiency, and preparation methods of autologous platelet concentrates in wound healing and periodontal regeneration, but it reports no new clinical findings.

This study found that Ift20 is essential for hair follicle stem cell identity and hair regrowth, and it regulates keratinocyte migration during wound healing through focal adhesion integrin recycling, independently of ciliogenesis.

This review highlights silk fibroin and its nanocomposites as promising materials for wound healing, addressing challenges in chronic wound treatment, especially in developing countries, and examines the obstacles in bringing silk-based products to market.

This literature review found that Long COVID is a complex condition involving multiple body systems, influenced by factors like pre-existing conditions and vaccination status, with differing manifestations and persistence, complicating diagnosis and treatment efforts.