135 citations,
December 2006 in “PLoS Medicine” Hyaluronate fragments can help reverse skin thinning by working with the CD44 receptor.
69 citations,
December 2015 in “BMC plant biology” Three genes in Arabidopsis are important for plant growth and development by affecting sugar attachment to proteins.
54 citations,
January 2023 in “Signal Transduction and Targeted Therapy” New therapies are being developed that target integrin pathways to treat various diseases.
45 citations,
October 2015 in “BMC Genomics” Chicken feather growth involves specific genes and shares similarities with hair development.
42 citations,
September 2012 in “PLoS ONE” Bezafibrate treatment improved skin and spleen health in aging mice but didn't extend lifespan.
16 citations,
September 2006 in “The Journal of Immunology” MILL molecules are unique immune proteins in mice that don't need TAP to appear on cell surfaces.
13 citations,
November 2017 in “Journal of Cellular and Molecular Medicine” The workshop discussed the role of a protein called calreticulin in health and disease, its potential as a treatment target, and its possible use as a disease marker.
2 citations,
July 2022 in “Frontiers in Cardiovascular Medicine” Forsythiasides have multiple health benefits but may cause pseudoallergic reactions, and more research is needed.
1 citations,
April 2023 in “Science Advances” High levels of ERK activity are key for tissue regeneration in spiny mice, and activating ERK can potentially redirect scar-forming healing towards regenerative healing in mammals.
1 citations,
February 2016 in “Cell Transplantation” Hair follicles have a more inactive cell cycle than other skin cells, which may help develop targeted therapies for skin diseases and cancer.
October 2023 in “Naunyn-Schmiedeberg's Archives of Pharmacology” Custom software found that common allergy drugs might have new uses for various conditions and could improve survival in some cancers.
December 2022 in “Frontiers in plant science” CCDC22 and CCDC93 are essential for root and root hair growth in Arabidopsis.
45 citations,
December 1991 in “Annals of the New York Academy of Sciences” ECM molecules are crucial for hair growth and development.
25 citations,
September 2013 in “Journal of thoracic oncology” Soy isoflavones can protect lung tissue from radiation damage.
4 citations,
September 2019 in “Biomedical Papers/Biomedical Papers of the Faculty of Medicine of Palacký University, Olomouc Czech Republic” CD2 might be a new treatment target for patchy alopecia areata.
3 citations,
May 2023 in “Precision clinical medicine” Researchers found four genes that could help diagnose severe alopecia areata early.
December 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” AP-2α and AP-2β proteins are essential for healthy adult skin and hair.
November 2022 in “Research Square (Research Square)” The research provides insights into hair follicle growth in forest musk deer by identifying key genes and pathways involved.
November 2022 in “Research Square (Research Square)” Keratin-associated proteins have ancient origins and were used for different purposes before being adapted for hair in mammals.
Wild African goats have genetic adaptations for surviving harsh desert conditions.
2 citations,
March 2023 in “BMC ecology and evolution” Some hair protein genes evolved early and were adapted for use in hair follicles.
137 citations,
October 2009 in “The American journal of pathology” Matriptase is crucial for keeping epithelial tissues healthy and functioning properly.
13 citations,
September 2018 in “Scientific Reports” The research found that a complex gene network, controlled by microRNAs, is important for hair growth in cashmere goats.
8 citations,
December 2017 in “Skin appendage disorders” WNT7A gene expression is higher in early stages of androgenetic alopecia, showing the role of WNT pathway, apoptosis, and inflammation in the disorder.
7 citations,
July 2008 in “Experimental Dermatology” The study concluded that a protein important for hair strength is regulated by certain molecular processes and is affected by growth phases.
5 citations,
February 2019 in “bioRxiv (Cold Spring Harbor Laboratory)” Rapamycin may help treat Leigh syndrome by targeting protein kinase C.
2 citations,
September 2022 in “Frontiers in veterinary science” Certain long non-coding RNAs are important for the growth of hair follicles in Inner Mongolian cashmere goats.
2 citations,
April 2021 in “International Journal of Molecular Sciences” The study concluded that changing the culture conditions can cause sika deer skin cells to switch from a flat to a 3D pattern, which is important for creating hair follicles.
January 2018 in “Stem cell biology and regenerative medicine” The nucleus is key in controlling skin growth and repair by coordinating signals, gene regulators, and epigenetic changes.
8 citations,
July 2022 in “Frontiers in plant science” pH changes are crucial for root hair growth because they affect enzymes and proteins that control the cell wall and growth.