research MendelVar: Gene Prioritization at GWAS Loci Using Phenotypic Enrichment of Mendelian Disease Genes
MendelVar is a tool that helps identify important genes by combining GWAS data with Mendelian disease information.
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180-210 / 1000+ results research Problem-Based Learning Tools: Pedagogy and Strategies for Implementing Project-Based Science
Problem-based learning in a biology class improved students' thinking and problem-solving skills.
research Logic-Based Modeling and Drug Repurposing for the Prediction of Novel Therapeutic Targets and Combination Regimens Against E2F1-Driven Melanoma Progression
Tadalafil and Finasteride may help treat aggressive melanoma.
research Deep Learning-Based Dermatological Condition Detection: A Systematic Review With Recent Methods, Datasets, Challenges, and Future Directions
Deep learning helps detect skin conditions and is advancing dermatology diagnosis and treatment.
research A Smart Deoxyribozyme-Based Fluorescent Sensor for In Vitro Detection of Androgen Receptor mRNA
Scientists made a sensor that can detect a specific type of RNA related to androgen receptors quickly and accurately.
research Prediction of Gain-of-Function and Loss-of-Function Mutations Using Combined Annotation Dependent Depletion
C-scores can help predict gain-of-function and loss-of-function mutations.
research Hydrogel Crosslinking Modulates Macrophages, Fibroblasts, And Their Communication During Wound Healing
Softer hydrogels help wounds heal better with less scarring.
research Hydrogel Composites for Multifunctional Biomedical Applications
Hydrogel composites have great potential in regenerative medicine, tissue engineering, and drug delivery.
research Commercial and Open-Source Systems
Commercial and open-source light sheet microscopy systems have advanced through engineer-scientist collaborations, improving imaging quality.
research Multi-Omics Analysis of Functional Substances and Expression Verification in Cashmere Fineness
The study concluded that the arachidonic acid pathway and the protein KRT79 play a role in determining the fineness of cashmere.
research Logic-Based Modeling and Drug Repurposing for the Prediction of Novel Therapeutic Targets and Combination Regimens Against E2F1-Driven Melanoma Progression
Cialis and Finasteride could be repurposed to treat aggressive melanoma.
research Possible Benefits of Androgenetic Alopecia Treatment
Many treatments for hair loss from androgenetic alopecia are giving people satisfying results.
research The Interdisciplinary Aspects of Aesthetic Medicine
New technologies and teamwork across specialties are changing facial aesthetics, offering personalized, non-surgical options.
research Histopathological Evaluation of Urethroplasty with Buccal Mucosa Graft: An Experimental Study in Rabbits
Buccal mucosa grafts work well for urethroplasty in rabbits.
research Dietary Vitamin A Dose Dependently Regulates BMP4 and WNT7A in Hair Follicles
Eating more vitamin A changes hair growth-related proteins in mice, affecting hair cycle stages.
research Psychodermatology in the UK: Psychological Impact and Integrated Treatments
Treating skin conditions with both psychological and dermatological care improves patient outcomes and can save costs.
research Water in Flow and Monk on Move - Stay Clean
The editorial welcomes the new editor of JCAS and discusses the journal's focus on quality research, global reach, and commitment to free access.
research Hair Replacement: Surgical and Medical
The book is a detailed guide on hair replacement surgery and its practices.
research Capillary Therapy of Male Androgenetic Alopecia with the Use of Low Power Laser Associated with Essential Oils
Low-power laser therapy with essential oils effectively promotes new hair growth in male pattern baldness.
research Inositol and FSH: A New Frontier for Androgenetic Alopecia Treatment
Inositol and folic acid treatment significantly reduced hair loss and other symptoms in patients with androgenetic alopecia, but more research is needed for confirmation.
research The Functional Organization of Cutaneous Low-Threshold Mechanosensory Neurons
Different hair follicles in the skin are innervated by unique combinations of mechanosensory neurons, crucial for touch sensation.
research Surface Modification and Endothelialization of Biomaterials as Potential Scaffolds for Vascular Tissue Engineering Applications
Improving artificial vascular grafts requires better materials and surface designs to reduce blood clotting and support blood vessel cell growth.
research Dermoscopy in General Dermatology: A Practical Overview
Dermoscopy is a useful tool for identifying features of skin conditions, but more research is needed to define its role in dermatology.
research Critical Stages of Hair Development and Pigmentation in the Mouse
Hair growth and pigmentation in mice involve specific stages crucial for research.
research HIV Pre-Exposure Prophylaxis in Transgender Women: A Subgroup Analysis of the iPrEx Trial
PrEP for HIV is less effective in transgender women mainly due to low adherence to the treatment.
research Self-Organizing and Stochastic Behaviors During the Regeneration of Hair Stem Cells
Hair stem cell regeneration is controlled by signals that can explain different hair growth patterns and baldness.
research Wound Healing and the Use of Medicinal Plants
Some medicinal plants can help heal wounds and may lead to new treatments.
research Ancient-Modern Concordance in Ayurvedic Plants: Some Examples
Modern science supports the use of some Ayurvedic plants for health, as ancient practices suggested.
research A Concise Review on Tissue Engineered Artificial Skin Grafts for Chronic Wound Treatment: Can We Reconstruct Functional Skin Tissue In Vitro?
Creating fully functional artificial skin for chronic wounds is still very challenging.
research Stem Cell Heterogeneity and Plasticity in Epithelia
Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.