This review discusses recent advances in using stem cells for skin repair and regeneration after severe burn injuries, but it reports no new clinical results.
87 citations
,
February 2004 in “Plastic and Reconstructive Surgery” In this study, researchers achieved complete reepithelialization and hair growth on a burn-injured scalp using a tissue-engineered dermal template with early micrograft hair follicle implantation.
December 2024 in “Macromolecular Bioscience” This study reports that a novel UV-based crosslinking process for collagen sponges significantly decreases crosslinking time compared to traditional methods, and supports effective cell proliferation and wound regeneration in a mouse model, without causing abnormal angiogenic or immune responses.
29 citations
,
September 2019 in “Stem Cells International” This study observed that a treatment combining platelet-rich fibrin and micrograft spray-on skin led to rapid and complete wound healing in both massive and chronic burn patients within an average of 7-10 days.
1 citations
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December 2006 in “Burns” New therapies for burn wounds show promise in reducing pain, infection risk, and improving healing and physical outcomes.
January 2012 in “Elsevier eBooks” This chapter reviews therapies for skin and corneal regeneration and hair loss, discussing various treatments but presenting no new research findings.
75 citations
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January 2011 in “Plastic and Reconstructive Surgery” This review discusses the use of dermal regeneration templates for treating burn injuries and other wounds, highlighting their effectiveness in reducing scars and aiding in regenerative processes, but reports no new clinical results.
1 citations
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January 2019 in “The International Journal of Lower Extremity Wounds” This study demonstrated in rodent models that artificial dermal template treatment can induce full-thickness skin regrowth including skin epidermis and adnexa without the need for autologous skin grafts.
26 citations
,
January 1994 in “Clinics in Dermatology” This article reviews advancements in burn care, emphasizing early wound excision's role in decreasing morbidity and mortality, but it reports no new clinical findings.
March 2025 in “International Journal of Trichology” This study reviews 3D printing's role in neurology, highlighting its potential to enhance hair restoration and scalp therapy through personalized solutions, while acknowledging the challenges of regulatory issues and the need for further research on long-term effects.
254 citations
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January 2012 in “Nature Reviews Molecular Cell Biology” This review discusses the role of stem cell progeny as integral components of stem cell niches, offering feedback that may influence different stem cell systems' microenvironments, but it presents no new research findings.
23 citations
,
June 2012 in “Molecular Biology Reports” This study found that human outer root sheath cells express VEGF receptor-2, and exogenous VEGF165 significantly stimulates their proliferation through activation of the ERK signaling pathway.
44 citations
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September 2019 in “The EMBO Journal” This study found that lymphatic vessels in mice are important for hair follicle development and organization, as their depletion blocks hair growth.
December 2013 in “The journal of investigative dermatology. Symposium proceedings/The Journal of investigative dermatology symposium proceedings” This article reviews the National Alopecia Areata Foundation's biennial research summits, aimed at advancing treatment development for alopecia areata, and reports no new results.
January 2024 in “Wiadomości Lekarskie” This study highlights the benefits of virtual surgical planning in orthognathic and facial trauma surgeries, noting its ability to enhance understanding of complex 3D anatomical relationships, reduce operation time, and integrate multidisciplinary approaches, including robotic assistance for real-time adjustments and customized implants.
11 citations
,
December 2024 in “Wound Repair and Regeneration” In this study, researchers created the WRAHPS Guidelines to standardize the reporting of preclinical wound healing studies, aiming to improve transparency, enable comparative analysis, and support the development of human clinical trials for wound healing disorders.
41 citations
,
January 2015 in “Burns & Trauma” This review discusses developments in tissue engineering for burn wound coverage and reconstructive surgery, reporting no new results but highlighting the need for further research into clinical effectiveness.
8 citations
,
May 2025 in “Biomolecules” This review highlights the evolution of forensic genetics from basic DNA analysis to complex genome-wide studies, enabling insights into personal traits, ancestry, and habits, and suggests future advancements through technologies like CRISPR and AI.
4 citations
,
September 2025 in “Pharmaceutics” This review highlights the potential of natural hydrogels as advanced wound dressings, emphasizing their capabilities in mimicking the extracellular matrix, supporting healing, and delivering therapeutic agents for chronic and infected wound care.
114 citations
,
October 2009 in “Gastroenterology” This review discusses zinc's role as an essential trace element in human nutrition, particularly its importance in total parenteral nutrition, and reports no new clinical results.
57 citations
,
July 2018 in “Scientific Reports” This study found that prevascularizing dermal matrices with adipose tissue-derived microvascular fragments improved vascularization and allowed earlier successful skin grafting in a bradythrophic wound model.
16 citations
,
December 2006 in “Expert Review of Dermatology” This review discusses the multifaceted roles of hair follicles in skin health, including potential contributions to skin neoplasias, and reports no new results.
55 citations
,
October 2009 in “Clinics in Plastic Surgery” Burn reconstruction improves with new techniques, materials, and tissue engineering.
79 citations
,
January 2015 in “Journal of Materials Chemistry B” This review discusses the development and future prospects of biomaterials for in situ tissue regeneration but reports no new research results; it underscores the importance of biomaterials in addressing tissue defects.
This study found that elastin-like recombinamer (ELR) wound dressings promote tissue regeneration and stability without rejection in ex vivo and in vivo models, indicating potential for hard-to-heal wound treatment.
This study demonstrated that cryogelation of human hair keratin allows the development of 3D scaffolds with tunable properties, supporting cell adhesion and proliferation for potential biomedical applications.
667 citations
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May 2008 in “Genes & Development” This review discusses the biochemical and biological functions of histone demethylases and their potential involvement in human diseases, including cancer, but reports no new findings.
555 citations
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July 2001 in “Genes & Development” This study found that Tcf3 and Lef1 differently regulate cell differentiation in multipotent skin stem cells, with Tcf3 promoting follicle-like features and Lef1, when modified, promoting sebocyte differentiation.
188 citations
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May 2009 in “Plant physiology” This study identified 19 specific genes involved in root hair growth and morphogenesis in Arabidopsis, using a combination of computational and experimental methods.
47 citations
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July 2005 in “British Journal of Dermatology” This study found no protective effect of topical calcipotriol on hair loss in chemotherapy patients, and the authors propose the term "atrophic telogen effluvium" for this type of hair loss.