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Both oral contraceptives reduced hirsutism in PCOS patients, but adding metformin showed no extra benefit.

The document concludes that more multidisciplinary research is needed to understand and treat PCOS, a condition that significantly affects women's health and quality of life.

Metformin helps improve menstrual irregularities and some hormone levels in PCOS patients, but not symptoms like excess hair, acne, or hair loss.

Aleglitazar and its major metabolite are safe enough to proceed to Phase 3 clinical trials.

High androgen levels can cause excessive hair growth and may indicate serious health issues, including heart disease and fertility problems.

New information suggests that metformin might help more women with PCOS and infertility, not just those with glucose issues.

Natural molecules like inositols, resveratrol, vitamins, and omega-3 fatty acids may help manage Polycystic Ovary Syndrome (PCOS), but their effects vary and need more exploration.

The conclusion is that a thorough approach is needed to diagnose and manage hyperandrogenism in teenage girls, recognizing its major psychological and health effects.

Lifestyle changes and clomiphene are first-line treatments for infertility in women with PCOS, with other options available if these fail.

Diagnosing PCOS in teenage girls is tricky and requires careful evaluation and management.

Recognizing new allergens can help reduce contact dermatitis cases.

Lower vaspin levels in the blood may indicate a better response to fertility treatment in women with PCOS.

Dietary changes, including weight loss and a balanced diet, are important for managing PCOS, especially in overweight women.

Myoinositol helps improve menstrual cycles and some skin issues in women with PCOS.

Female relatives of PCOS patients have a higher chance of showing PCOS symptoms.

HSD3B1 gene variant and being overweight linked to hair loss in women with polycystic ovary syndrome.

*Acorus calamus* has many medicinal benefits but needs more safety research.

Amla is a natural remedy with many health benefits, including antiviral and antibacterial properties.

PCOS often leads to sleep problems, especially obstructive sleep apnea, affecting overall health.

Girls with PCOS and menstrual disorders have notably higher androgen hormone levels.

Fish oil improves skin health in people with diabetes and high cholesterol.

Obese women with PCOS show a male-like pattern in certain fat tissue gene expressions.

Lifestyle changes like diet and exercise are crucial for managing PCOS.

Selenium is essential for health, but too much or too little can cause problems; blood selenium levels are a good measure of intake.

Men with severe hair loss may have a higher risk of heart disease.

Flutamide combined with a low-dose birth control pill effectively reduces excessive hair growth in women with polycystic ovarian disease.

Sex hormones may affect COVID-19 severity, with estrogen possibly reducing risk and testosterone potentially increasing it.

The WNT signaling pathway is important in many diseases and targeting it could offer new treatments.

More severe hair loss links to thicker heart fat, suggesting possible heart disease risk.

While PCOS might increase the risk of heart disease, there's not strong evidence to prove it causes earlier heart problems.