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This perspective discusses Villani et al.'s findings on the role of the IGF regulatory protein Igfbp2 in basal cell carcinogenesis and highlights potential therapeutic and preventive targets, while raising questions about the cell of origin.

This review examines adipose-derived stem cells as a promising therapy for alopecia but reports no new clinical results, discussing their potential mechanisms and the challenges faced in treatment development.

This study found that intrauterine administration of botulinum toxin A improved endometrial environment and receptivity in a murine model of thin endometrium through mechanisms involving IGFBP3 and osteopontin.

In this study, treatment with human follicular keratinocyte-conditioned media improved the trichogenicity of cultured dermal cells by activating key signalling pathways, suggesting its potential use in cell therapy for hair loss.

The article concludes that hormonal therapy is an effective long-term acne treatment, even for those without hormonal imbalances.

This review discusses the growth factors produced by adipose tissue-derived stem cells that are associated with hair growth stimulation and reports no new clinical findings.

This review explores the potential impact of hormonal changes during aging on benign prostate hyperplasia-related urinary symptoms and metabolic syndrome, highlighting the hypothesis of a male PCOS-equivalent but reports no new clinical results.

This review discusses the complex relationship between anabolic substances and colorectal cancer risk, reporting ambiguous findings on their carcinogenic properties, potential synergy with risk factors, and protective roles.

This study summarizes the signaling molecules and extracellular components involved in epithelial–mesenchymal interactions, enhancing our understanding of hair follicle regeneration and skin wound healing, but reports no new experimental results.

This study found that ovine dermal papilla cells exhibit robust aggregation and alkaline phosphatase activity, regulated by Wnt/β-catenin signaling, providing insights for improving wool performance and hair regeneration therapies.

This review examines platelet-enriched plasma as a potential new treatment for androgenetic alopecia but reports no new clinical results; the authors suggest standardizing its use based on alopecia stages.

This review discusses platelet-rich plasma as a treatment for androgenetic alopecia and explains its mechanisms, but presents no new clinical results.

This study discusses how redox imbalance, specifically through reduced Insulin-like Growth Factor-1 mediated by the transcription factor JunB and sphingolipid metabolism changes, contributes to skin aging by depleting stem cell pools and altering the extracellular matrix, ultimately impacting skin integrity and function.

In this study, researchers found that wool growth regulation is likely achieved through endocrine growth factors, with various growth factors inhibiting fibre growth in vitro.

This study found that simvastatin interfered with insulin-induced VEGF expression and keratinocyte proliferation during skin repair in mice, effects that could be reversed by mevalonate.

This review discusses the clinical features and therapeutic goals for teenagers with PCOS, emphasizing the need for further research into its causes and potential long-term health risks, but reports no new clinical results.

This research provides insights into how keratin hydrogels, modified to control disulfide crosslinking, may function as a treatment platform for bone injuries.

This review explores the potential (neuro-)endocrine influences on hair follicle epithelial stem cell biology and emphasizes the need for more systematic research, but it provides no new empirical results.

This article discusses the importance of lifestyle management, like physical activity and healthy habits, in mitigating polycystic ovarian syndrome's impact and reports no new clinical findings.

This paper discusses the importance of early diagnosis and treatment of polycystic ovarian syndrome to potentially reduce long-term complications like diabetes, hypertension, and heart disease, but reports no new clinical outcomes.

This study found that BeauTop, a supplement containing several traditional Chinese herbs, may promote hair growth in mice with alopecia, potentially by modulating EGF and FGF-7 levels.

This study found that BNC2 is critical for hair follicle regeneration and other developmental processes, as Bnc2−/− mice exhibit incomplete hair follicle development and developmental defects, and BNC1 cannot substitute for BNC2.

This review discusses the interplay between endocrinology and dermatology in PCOS, highlighting the roles of hyperandrogenism, insulin resistance, and chronic inflammation in related skin conditions, but reports no new clinical results.

This infographic reviews the pathophysiology and complications of PCOS, illustrating how genetic and environmental factors contribute to its development, and highlights associated metabolic and neuroendocrine effects.

This article discusses the signs, symptoms, and associated risks of polycystic ovary syndrome, without providing new clinical results; it emphasizes the link between being overweight and increased metabolic risks.

This review discusses the causes and management of hirsutism, recommending low-dose oral contraceptives with flutamide over cyproterone-containing preparations, but reports no new clinical findings.

In this study, researchers found that girls aged 4-8 years with isolated premature thelarche had significantly advanced bone age, with obesity and elevated serum IGF-1 SDS and DHEAS SDS being key independent risk factors.

This study found that girls with isolated premature thelarche, confirmed by GnRH stimulation test, aged 4-8 years, may have significantly advanced bone age, with obesity and serum IGF-1 and DHEAS levels being key risk factors.

This study demonstrated that water-soluble peptides from egg yolk, termed "hair growth peptide," stimulated human hair follicle cell growth and improved hair growth in female pattern hair loss.

This review discusses lifestyle interventions and dietary modifications for managing PCOS symptoms but reports no new clinical results; the authors emphasize the importance of early diagnosis and management to prevent associated health issues.