The conclusion is that there's a link between high testosterone levels, insulin resistance, and certain skin conditions, regardless of obesity.
February 2023 in “Clinical, Cosmetic and Investigational Dermatology” Higher leptin and lower vitamin D levels may contribute to male pattern baldness.
March 2022 in “Benha Journal of Applied Sciences” AGA patients have higher insulin resistance and serum progranulin levels, suggesting a link to metabolic issues.
September 2020 in “Benha Journal of Applied Sciences” Higher myostatin and insulin resistance are linked to androgenetic alopecia.
February 2020 in “Benha Journal of Applied Sciences” Higher Galectin-3 levels are linked to insulin resistance and may predict androgenetic alopecia severity.
January 2020 in “Menoufia Medical Journal” IGF-1R may play a role in female hair loss and could be a treatment target.
April 2018 in “Journal of Investigative Dermatology” Finasteride helps female-pattern hair loss.
February 2017 in “Clinical dermatology open access journal” Men with early hair loss may have higher insulin resistance and should be checked for related health issues.
January 2017 in “IP Indian journal of clinical and experimental dermatology” Early-onset male baldness is not linked to insulin resistance, but is significantly associated with metabolic syndrome.
January 2016 in “Indian journal of clinical and experimental dermatology” Early hair loss in young males may not be clearly linked to insulin resistance or metabolic syndrome.
There's no clear link between female pattern hair loss, insulin resistance, and metabolic syndrome.
May 2015 in “Endocrine Abstracts” Both finasteride and metformin effectively treat PCOS by reducing hormone levels and insulin resistance.
23 citations,
March 1994 in “Fertility and sterility” Most patients improved with oral contraceptives, but some needed additional treatment.
19 citations,
April 2015 in “Stem Cells” Pro-IGF-II improves muscle repair in old mice.
January 2019 in “Current research in diabetes & obesity journal” A woman with type 2 diabetes developed alopecia areata, suggesting a link between the two autoimmune conditions.
7 citations,
August 2017 in “European journal of endocrinology” Mutations in the POC1A gene can cause a unique form of extreme insulin resistance and short stature.
5 citations,
June 2018 in “Journal of Diabetes, Metabolic Disorders & Control” Women with PCOS may have higher bad cholesterol and are at risk for blood sugar issues; lifestyle changes are recommended.
1 citations,
November 2023 in “Journal of neurology” A patient with a nerve disorder died from infection complications after developing insulin resistance from a treatment.
Clinicians should look for skin issues, sleep problems, cognitive changes, and food cravings as signs of insulin resistance.
A 9-year-old girl developed type 1 diabetes and alopecia after being treated for a rare kidney disease.
January 2024 in “Archives of Endocrinology and Metabolism” A new gene mutation causes insulin resistance in a girl and her mother.
December 2010 in “Médecine des Maladies Métaboliques” The Accu-Chek FlexLink Plus and Accu-Chek LinkAssist Plus make insulin pump use safer, simpler, and more comfortable.
The document concludes that Syndromes of Severe Insulin Resistance are rare disorders with limited treatment options.
50 citations,
January 2018 in “Acta physiologica” Working night shifts for four days can lower the body's ability to use insulin, which may increase the risk of type 2 diabetes.
36 citations,
March 2005 in “Biotechnology and Bioengineering” A new method speeds up insulin amyloid fibril growth, useful for studying diseases.
15 citations,
July 2012 in “Biological trace element research” Higher hair calcium to magnesium ratios and lower chromium levels in hair may indicate insulin resistance in Korean men.
11 citations,
August 2020 in “Diabetes” Testosterone helps human pancreatic cells increase insulin release.
Testosterone in human pancreas cells boosts insulin production.
Testosterone in our bodies helps increase insulin secretion from the pancreas.
November 2001 in “Hair transplant forum international”