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Laser treatment improves hair density and increases growth factors in androgenetic alopecia.

L-PGDS has specific binding sites for its functions and could help in drug delivery system design.

mTOR signaling helps activate hair stem cells by balancing out the suppression caused by BMP during hair growth.

Androgens slow hair growth by altering Wnt signaling in balding cells.

Metformin should be used for PCOS mainly in those with glucose intolerance, and has limited benefits for infertility or hirsutism.

The research found different metabolism changes in PCOS patients and suggested new potential markers for diagnosing PCOS with or without insulin resistance.

Undariopsis peterseniana extract helps hair grow by activating certain cell growth pathways and could be a new treatment for hair loss.

Phaeodactylum tricornutum extract helps hair follicle cells grow by activating the ERK1/2 pathway.

TLR2 is important for hair growth and can be targeted to treat hair loss.

Insulin resistance is linked to high male hormone levels in women, often seen in those with PCOS.

Pilose antler extracts help hair growth by activating hair follicle stem cells.

TGF-β signaling is crucial for stem cell maintenance, differentiation, and has implications for cancer treatment.

Dermal exosomes with miR-218-5p boost hair growth by controlling β-catenin signaling.

The document explains how to create detailed biological pathways using genomic data and tools, with examples of hair and breast development.

Targeting the HEDGEHOG-GLI1 pathway could help treat keloids.

Skin aging is caused by stem cell damage and can potentially be delayed with treatments like antioxidants and stem cell therapy.

Testosterone helps human pancreatic cells increase insulin release.

Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.

Skin diseases linked to insulin resistance should be managed to prevent diabetes and reduce heart disease risk.

People with PCOS, especially if obese, often have NAFLD, linked to obesity, insulin resistance, and high androgen levels.

FGF signaling is a promising target for developing treatments for wounds, metabolic diseases, and cancer.

Androgen receptor signaling causes early aging of cells important for hair growth by damaging their DNA.

Polycystic Ovary Syndrome (PCOS) is a hormonal disorder in women that can cause infertility and other health issues, and it may be improved by treatments that increase insulin sensitivity.

Adult esophageal cells can start to become like skin cells, with a key pathway influencing this change.

Tetrahydroxystilbene Glucoside may help prevent hair loss by blocking certain pathways that lead to cell death.

Melatonin helps Cashmere goats grow more hair by affecting certain genes and cell pathways.

Some herbs and their components might help treat hair loss by affecting various biological pathways, but more research and regulation are needed.

Phosphatidic acid may help hair grow by affecting cell growth pathways.

A specific RNA molecule, circCOL1A1, affects the growth and quality of goat hair by interacting with miR-149-5p and influencing cell growth pathways.

The document concludes that understanding genetic mutations in the PI3K-AKT-mTOR pathway can lead to better diagnosis and treatment for certain genetic skin disorders.