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    Glossary Insulin Resistance

    condition where cells don't respond well to insulin

    Insulin Resistance (IR) is a condition where the body's cells become less responsive to the hormone insulin, which is crucial for regulating blood sugar levels. As a result, the pancreas produces more insulin to compensate, leading to higher insulin levels in the blood and potentially progressing to type 2 diabetes. This condition is often associated with obesity, physical inactivity, and genetic factors.

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    1. Abdominal Fat Quantity and Distribution in Women with Polycystic Ovary Syndrome and Extent of Its Relation to Insulin Resistance The Journal of Clinical Endocrinology and Metabolism · 2007 · 270 citations
    2. Polycystic Ovary Syndrome, Insulin Resistance, and Obesity: Navigating the Pathophysiologic Labyrinth International journal of reproductive medicine · 2014 · 222 citations
    3. Polycystic ovarian syndrome: Correlation between hyperandrogenism, insulin resistance and obesity Clinica Chimica Acta · 2019 · 195 citations
    4. The influence of androgens on insulin resistance Fertility and sterility · 1984 · 135 citations
    5. Early androgenetic alopecia as a marker of insulin resistance The Lancet · 2000 · 115 citations
    6. Hyperandrogenism and insulin resistance modulate gravid uterine and placental ferroptosis in PCOS-like rats Journal of Endocrinology · 2020 · 104 citations
    7. Prevalence of Type II diabetes mellitus and insulin resistance in parents of women with polycystic ovary syndrome Diabetologia · 2002 · 100 citations
    8. 5α-Reductase Type 1 Deficiency or Inhibition Predisposes to Insulin Resistance, Hepatic Steatosis, and Liver Fibrosis in Rodents Diabetes · 2014 · 93 citations
    9. Metformin improves polycystic ovary syndrome symptoms irrespective of pre-treatment insulin resistance European journal of endocrinology · 2007 · 91 citations
    10. Insulin Resistance and Skin Diseases The Scientific World Journal · 2015 · 71 citations
    11. Polycystic ovary syndrome: insight into pathogenesis and a common association with insulin resistance Clinical Medicine · 2015 · 62 citations
    12. Polycystic ovary syndrome: insight into pathogenesis and a common association with insulin resistance Clinical Medicine · 2016 · 61 citations
    13. Polycystic ovary syndrome and insulin-resistant hyperinsulinemia Journal of the American Academy of Dermatology · 2001 · 60 citations
    14. Associaton of Insulin Resistance Linked Diseases and Hair Loss in Elderly Men. Finnish Population-based Study Central European Journal of Public Health · 2006 · 55 citations
    15. Genetic Defects in Human Pericentrin Are Associated With Severe Insulin Resistance and Diabetes Diabetes · 2011 · 53 citations
    16. Androgenetic alopecia and insulin resistance in young men Clinical Endocrinology · 2008 · 50 citations
    17. Hair Loss, Insulin Resistance, and Heredity in Middle-aged Women. a Population-based Study European journal of cardiovascular prevention & rehabilitation · 2003 · 49 citations
    18. Coronavirus and Obesity: Could Insulin Resistance Mediate the Severity of Covid-19 Infection? Frontiers in Public Health · 2020 · 49 citations
    19. Putative role for insulin resistance in depression risk in polycystic ovary syndrome Fertility and Sterility · 2015 · 46 citations
    20. Autotaxin-LPA signaling contributes to obesity-induced insulin resistance in muscle and impairs mitochondrial metabolism Journal of Lipid Research · 2018 · 45 citations
    21. The evaluation of endothelial function with flow-mediated dilatation and carotid intima media thickness in young nonobese polycystic ovary syndrom patients; existence of insulin resistance alone may not represent an adequate condition for deterioration of endothelial function Fertility and Sterility · 2008 · 44 citations
    22. Acanthosis nigricans, insulin resistance and cutaneous virilism British Journal of Dermatology · 1988 · 43 citations
    23. Insulin resistance and obesity among infertile women with different polycystic ovary syndrome phenotypes Scientific Reports · 2017 · 42 citations
    24. The investigation of insulin resistance and metabolic syndrome in male patients with early-onset androgenetic alopecia European Journal of Dermatology · 2011 · 42 citations
    25. Role of insulin resistance and diet in acne Indian Journal of Dermatology, Venereology and Leprology · 2013 · 39 citations
    26. Mechanisms Involved in the Relationship between Vitamin D and Insulin Resistance: Impact on Clinical Practice Nutrients · 2021 · 37 citations
    27. Resistance to the Insulin and Elevated Level of Androgen: A Major Cause of Polycystic Ovary Syndrome Frontiers in Endocrinology · 2021 · 36 citations
    28. Androgenetic alopecia and insulin resistance: are they truly associated? International Journal of Dermatology · 2011 · 35 citations
    29. Higher PDCD4 expression is associated with obesity, insulin resistance, lipid metabolism disorders, and granulosa cell apoptosis in polycystic ovary syndrome Fertility and Sterility · 2016 · 34 citations
    30. Androgenetic alopecia, metabolic syndrome, and insulin resistance: Is there any association? A case-control study Indian Dermatology Online Journal · 2014 · 34 citations