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Genetic variation in the androgen receptor gene mainly causes early-onset hair loss, with maternal inheritance playing a key role.

Testing for CAG repeat polymorphism in the androgen receptor gene is not currently recommended for managing hypogonadism.

Certain genetic variations in the AR and ERβ genes can affect androgen levels in women.

Longer CAG repeat lengths in the androgen receptor gene are linked to higher testosterone levels in women with PCOS.

Certain gene patterns in breast cancer are linked to how active hormone receptors are and could affect patient survival.

A patient with myotonic dystrophy had several autoimmune disorders and thyroid cancer, suggesting a possible link between these conditions.

A certain gene variant may increase the risk of polycystic ovary syndrome in Chinese women.

AGA causes hair loss by shrinking hair follicles due to DHT binding, and can be treated with finasteride and minoxidil.

FGF signaling is a promising target for developing treatments for wounds, metabolic diseases, and cancer.

Androgens like testosterone are important hormones for both men and women, made differently in each sex and affecting the body by regulating genes and quick interactions with cell components.

Effective treatments for spinal and bulbar muscular atrophy are not yet available; more research is needed.

Testosterone significantly affects sexual desire in both men and women, but its impact on women is more complex and influenced by psychological factors.

Anorexia Nervosa and Bulimia Nervosa are complex eating disorders with increasing incidence among young females, significant morbidity, and varying mortality rates, requiring more research for better treatment.

The document concludes that mouse models are crucial for studying hair biology and that all mutant mice may have hair growth abnormalities that require detailed analysis to identify.

The skin's ability to produce hormones is linked to various skin conditions, and better understanding this process could lead to new treatments.

Potassium channel openers show promise for treating heart disease and other conditions, but more research is needed to fully understand their effects and safety.

New compounds may help treat prostate cancer by reducing cell growth.

Topical drugs and near-infrared light therapy show potential for treating alopecia.

Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.

The document concludes that alopecia has significant social and psychological effects, leading to a market for hair loss treatments.

Hair disorders are caused by a complex mix of biology, genetics, hormones, and environmental factors, affecting hair growth and leading to conditions like alopecia.

Certain proteins and their receptors are more active during the growth phase of human hair and could be targeted to treat hair disorders.

The document concludes that accurate diagnosis of male and female gonadal disorders is crucial for effective treatment and better patient outcomes.

PPARγ is essential for maintaining healthy skin, controlling inflammation, and ensuring proper skin barrier function.

Mutations in the AR gene cause hair thinning and loss.

The document concludes that while some organisms can regenerate body parts, mammals generally cannot, and cancer progression is complex, involving mutations rather than a strict stem cell hierarchy.

Cancer development is like natural selection, involving mutated cells and environmental factors.

GLI1 might protect against the start of skin cancer and is not linked to cancer severity.

Rapamycin treatment helps with mitochondrial disease by reducing PKC levels.

Some natural compounds may help overcome drug resistance in certain cancers, but more research is needed.