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Tacrolimus is effective for various skin conditions with fewer side effects than cyclosporine.

The document concludes that sexual and psychiatric side effects from 5-alpha-reductase inhibitors are reported, but more high-quality research is needed to understand how often they occur.

Some Middle Eastern plants may help treat diabetes and could be alternatives to current drugs, but more research is needed.

Hormone therapy for transgender females increases the risk of blood clots and requires careful dosing, monitoring, and lifelong management.

Testosterone therapy may slightly improve sexual function in postmenopausal women, but its long-term safety is unknown.

Skin problems can be linked to sexual abuse, requiring careful medical and psychological evaluation.

The document concludes that managing non-classical congenital adrenal hyperplasia in females requires personalized treatment, genetic counseling, and a team of specialists.

Better-designed, long-term studies are needed to optimize treatment for trichotillomania and trichophagia.

Women with high androgen levels may have more severe COVID-19 symptoms.

High-content screening is useful for finding new treatments for rare diseases and has led to FDA-approved drugs.

Healthcare workers in Turkey experienced more skin problems due to frequent handwashing and wearing masks and gloves during the COVID-19 outbreak.

The enzyme 5α-reductase is key in causing psychotic-like effects from sleep deprivation.

The document concludes that there is a significant lack of reporting on the sex and age of cells in skin research, which could affect clinical trials and treatments.

Minoxidil lowers blood pressure more effectively but has more side effects, so try hydralazine first.

Long COVID patients may have hormonal imbalances linked to their symptoms.

Using anabolic androgenic steroids can cause serious, lasting health problems in many parts of the body.

Dapsone improved pustular psoriasis in patients who didn't respond to other treatments and is considered a well-tolerated option.

The leaves of Platycladus orientalis have potential health benefits but require more research for safety and understanding how they work.

Consider benefits and risks of new alopecia treatments for safety.

Dermatologists should screen for and manage psychological issues in patients with skin conditions to improve their quality of life.

Liposomal anthracyclines are effective and safer for treating multiple myeloma, especially in elderly patients.

The Brazilian Society of Dermatology agrees that oral isotretinoin is effective for acne and other skin conditions, and it's safe when monitored, but more research is needed on dosing and duration.

DHEA may help with sexual function when used intravaginally by menopausal women but is similar to hormone therapy in other aspects and might cause more side effects like acne and hair loss.

Stress can worsen skin conditions and affect mental health, so doctors should include stress management in skin treatment.

Testosterone implants in women require pharmacological dosing to be effective and are generally safe and well-tolerated.

Testosterone therapy helped 63% of androgen-deficient women grow scalp hair, but more research is needed.

Taking L-tryptophan supplements might cause a condition similar to scleroderma in some people, which can get better after stopping the supplement and starting corticosteroid therapy.

Dutasteride does not impair mental function in elderly men with enlarged prostate.

Personalized treatment with inhibitors, minoxidil, and laser therapy helps hair loss.

High doses of tryptophan may cause eosinophilic fasciitis.