142 citations
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December 1991 in “Antimicrobial Agents and Chemotherapy” This study reported that continuous intravenous dextran sulfate was toxic and ineffective as a treatment for symptomatic HIV infection, as it did not improve surrogate markers and caused significant side effects.
64 citations
,
August 1999 in “The American journal of medicine” This study found that while a transscrotal testosterone patch increases serum testosterone levels in hypogonadal men with AIDS and weight loss, it does not improve weight, body cell mass, or quality of life.
60 citations
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September 2004 in “Pediatric Dermatology” In this study, a 10-year-old girl developed vitiligo and psoriasis during IFN-alfa treatment for chronic hepatitis B, with neither condition improving after stopping the therapy.
49 citations
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February 2020 in “Scientific reports” In this study, the Selenium-Chitosan-Mupirocin nanohybrid system significantly enhanced wound healing in a rat model of diabetic wound infection compared to the control, suggesting potential for treating mild diabetic wounds.
41 citations
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August 2007 in “European Journal of Gastroenterology & Hepatology” This case report documents a reversible instance of complete body hair loss (alopecia universalis) in a patient undergoing chronic hepatitis C treatment with pegylated interferon alpha-2b and ribavirin, with hair regrowth observed within three months after therapy completion.
39 citations
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January 2008 in “World Journal of Gastroenterology” This report documents the first known case of acute inflammatory demyelinating polyneuropathy potentially linked to pegylated interferon-alpha 2a in a woman undergoing treatment for chronic hepatitis C.
35 citations
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January 2022 in “Clinical Infectious Diseases” This study found that healthcare workers with a positive COVID-19 test reported long COVID symptoms more frequently than negative controls, while prior physical activity was linked to reduced neurocognitive and fatigue symptoms.
24 citations
,
December 2020 in “Kardiologiia” This study found that combining bromhexine and spironolactone was effective in improving clinical outcomes and reducing viral load or hospitalization duration in patients with mild to moderate COVID-19.
21 citations
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January 2021 in “Therapeutic Advances in Endocrinology and Metabolism” The researchers suggest that testosterone levels might influence COVID-19 susceptibility and severity, with low levels potentially protecting against infection but possibly worsening severe disease due to cytokine storm activation.
14 citations
,
April 2022 in “Molecules” This study found that pulmonary delivery of cepharanthine significantly improved bioavailability and may provide protective effects against pulmonary fibrosis related to COVID-19 infection in a rat model.
12 citations
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November 2021 in “Journal of Clinical Medicine” This study reported that 70.1% of kidney transplant recipients experienced persistent symptoms of post-COVID-19 syndrome six months after infection, with older patients and those with more comorbidities being more affected.
10 citations
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February 2022 in “Epidemiologia” This study reported that about one-third of post-COVID-19 patients experienced long-term symptoms, with women, older individuals, smokers, and those with specific blood groups at higher risk for complications.
9 citations
,
February 2024 in “mBio” This study found that biliverdin beta and delta, metabolites of heme, play a critical role in Pseudomonas aeruginosa iron acquisition and cooperative behaviors, which are crucial for the bacterium's long-term infection in cystic fibrosis patients, suggesting potential targets for new therapies.
8 citations
,
September 2023 in “International Journal of Nanomedicine” In this study, researchers developed an in vitro airway-organoid model using human lung-derived cell lines on RADA16-I hydrogels to serve as a potential tool for studying adenovirus isolation, pathogenesis, and antiviral drug screening.
7 citations
,
June 2021 in “JAAD Case Reports” This article reviews the cutaneous manifestations of COVID-19, highlighting their potential as early indicators of infection, and reports no new clinical results.
5 citations
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January 2024 in “Journal of Primary Care & Community Health” This study observed that the severity of long COVID symptoms varies among patients and sociodemographic and clinical factors affect the likelihood of experiencing symptoms for more than a year. Understanding these factors may optimize management and improve patient outcomes.
5 citations
,
October 2022 in “Materials Research Express” This study found that zinc oxide and fucoidan-loaded chitosan nanofiber scaffolds may enhance wound healing and provide antibacterial protection against common surgical pathogens in vitro.
4 citations
,
May 2025 in “npj Parkinson s Disease” This study identified peripheral myeloid cells as the earliest dysregulated immune cells in PINK1 KO mice with Parkinson’s-like symptoms following intestinal infections, suggesting that PINK1 regulates gut immune functions linked to early Parkinson’s disease mechanisms.
4 citations
,
December 2023 in “Research Review” In this retrospective cohort study, researchers reported that 77% of 300 COVID-19 survivors experienced long COVID-19 symptoms such as fatigue and hair loss, with symptoms more likely in females, younger age groups, and hospitalized patients.
3 citations
,
March 2024 in “Viruses” This study found that γδ T cells in the skin contribute to wound healing after vaccinia virus infection by promoting cytokine and growth factor induction, without affecting virus replication control.
3 citations
,
November 2022 in “Baghdad Journal of Biochemistry and Applied Biological Sciences” This study found that renin and d-dimer levels were significantly higher in PCOS patients, particularly those also infected with COVID-19, compared to non-PCOS women.
1 citations
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October 2022 in “Cureus” This study reported that over half of recovered COVID-19 patients in Saudi Arabia experienced hair loss, with factors such as high fever, female gender, and prior hair loss significantly associated with incidence of acute telogen effluvium.
1 citations
,
September 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that skin-resident and recruited γδ T cells play a crucial role in an early wound healing response following cutaneous vaccinia virus infection, rather than in controlling virus replication.
1 citations
,
May 2019 in “PubMed” This report presents a case of a female with PCOS treated with metformin who developed hyperuricemia, severe joint and neurological pain, and later experienced a hypersensitivity reaction to benzathine benzyl penicillin.
1 citations
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March 2019 in “KnE life sciences” This case report suggests that human dermal papillae conditioned media may accelerate wound healing in congenital aplasia cutis due to varicella infection.
This case report describes how anifrolumab, used beyond trial-eligible populations, led to significant clinical and serological recovery in a 45-year-old woman with organ-threatening systemic lupus erythematosus complicated by infection and resistant to conventional treatments like cyclophosphamide and rituximab.
November 2025 in “International Society of Hair Restoration Surgery” This article reviews immediate post-operative folliculitis, emphasizing its self-limiting nature and differentiation from infective folliculitis, but it reports no new clinical findings.
January 2025 in “The World Journal of Men s Health” In this study, autologous intratesticular PRP injection was found to be a feasible and well-tolerated procedure with low complication rates and quick recovery, but the authors indicated that current evidence is insufficient to confirm its effectiveness for mTESE.
October 2023 in “Journal of Preventive Diagnostic and Treatment Strategies in Medicine” This study found that women experiencing hair loss after recovering from COVID-19 had significantly lower Vitamin D and ferritin levels and higher testosterone and triglyceride levels compared to those without hair loss, indicating a potential link between these factors and the condition.
This study found that dermoscopy combined with calcium fluorescent white staining effectively aided in the early diagnosis and treatment evaluation of tinea capitis by highlighting specific hair changes and fluorescent patterns associated with different dermatophyte infections in a sample of 20 patients.