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Certain defective glucocorticoid receptor mutants move faster inside cell nuclei and work less effectively.

TPA promotes hair growth by increasing stem cell activity and activating specific cell signals.

Future research on ectodysplasin should explore its role in diseases, stem cells, and evolution, and continue developing treatments for genetic disorders like hypohidrotic ectodermal dysplasia.

Polyamines are important for hair growth, but more research is needed to understand their functions and treatment potential.

Amenorrhea is when a woman doesn't have periods, with primary amenorrhea starting by age 15 or within five years of breast development, and secondary amenorrhea when periods stop for three months. It affects 3-4% of women not pregnant, breastfeeding, or in menopause, mainly due to polycystic ovary syndrome, hypothalamic amenorrhea, hyperprolactinemia, and ovarian failure.

15-lipoxygenase helps keep skin healthy by reducing inflammation.

The document provides advice on how to recognize and treat skin-related side effects of cancer drugs known as EGFR inhibitors.

Adult stem cells are important for tissue repair and have therapeutic potential, but more research is needed to fully use them.

Hair disorders are caused by a complex mix of biology, genetics, hormones, and environmental factors, affecting hair growth and leading to conditions like alopecia.

Hair can regrow in large wounds through a process similar to how hair forms in embryos, and understanding this could lead to new treatments for hair loss or scarring.

Proper control of β-catenin activity is crucial for development and preventing diseases like cancer.

Certain fats in the skin help control inflammation and health, and changing these fats through diet or supplements might treat skin inflammation.

Gene therapy, especially using atoh1, shows promise for creating functional sensory hair cells in the inner ear, but dosing and side effects need to be managed for clinical application.

Activin activation in skin cells speeds up wound healing without affecting scar quality.

TAF4 is important for skin cell growth and helps prevent skin cancer in mice.

Certain microRNAs are linked to various skin diseases and could be used to diagnose and treat these conditions.

Dutasteride protects dopamine neurons in Parkinson's mice, but Finasteride doesn't.

The skin and thymus develop similarly to protect and support immunity.

Researchers created a mouse model for Cushing's syndrome to study glucocorticoid excess and potential treatments.

SCF and ET-1 together significantly increase skin pigmentation and melanin production.

Finasteride and dutasteride reduce unwanted movements from Parkinson's disease treatment by normalizing certain brain signals.

AIRE-deficient rats developed severe autoimmune disease similar to APECED, useful for testing treatments.

Infertile men are more likely to produce sperm with abnormal chromosome numbers, which can affect pregnancy success and embryo health.

Certain gene variations are not a major cause of male infertility in Nigerian men.

ISCK03 stops melanin production in human melanoma cells and lightens skin color in mice and guinea pigs.

Calcium is important for stem cell function and maintenance, especially in blood and skin cells.

Cholesterol balance is important for hair health, and problems with it can lead to hair loss conditions.

The document concludes that certain mutations may contribute to the inflammation in hidradenitis suppurativa and suggests that targeting TNFα could be a treatment strategy.

Blocking Wnt/β-catenin signaling with EGF receptor is necessary for proper hair growth.

R-spondins and their receptors help increase bone growth and may be used to treat bone loss diseases.