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The document concludes that mouse models are helpful but have limitations for skin wound healing research, and suggests using larger animals and genetically modified mice for better human application.

Some drugs can cause rare but potentially deadly skin reactions, and early treatment and avoiding the drug again are key.

Vitamin D receptor interacts with certain dietary components to help prevent diseases and regulate hair growth.

Wnt signaling is crucial for pigmented hair regeneration by controlling stem cell activation and differentiation.

Teriflunomide helps reduce multiple sclerosis symptoms and is safe for most patients.

Exposure to too much androgen before birth might cause polycystic ovary syndrome later in life.

Melatonin in the skin helps protect against damage from stress and UV rays, and could be used to treat certain skin conditions.

The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.

Human skin can make serotonin and melatonin.

Wnt1/βcatenin signaling is crucial for heart repair after injury.

TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.

The document concludes that the fast-growing direct-to-consumer genetic testing market lacks sufficient regulation, posing risks to consumers due to questionable test quality and accuracy.

Finasteride doesn't effectively treat hair loss in postmenopausal women.

Fat cells help recruit healing cells and build skin structure during wound healing.

A protein from certain immune cells is key for new hair growth after skin injury in mice.

The report recommends personalized treatment for women's sexual dysfunctions and more research on effective therapies.

Chitin and chitosan are useful in cosmetics for oral care, haircare, and skincare, including UV protection and strength improvement.

Acne affects most teenagers and can continue into adulthood, with various treatments available that show improvement but have concerns like antibiotic resistance and side effects.

Eph receptors and ephrins may be promising targets for treating diseases, but more understanding is needed for effective and safe therapies.

5% and 2% minoxidil solutions effectively promote hair growth and reduce hair loss, with 5% being slightly more effective but having more side effects.

Minoxidil and finasteride treat hair loss in men, while minoxidil treats hair loss in women.

Keratins are crucial for cell structure, growth, and disease risk.

The skin is a complex barrier for drug penetration, but understanding its structure and interactions can improve drug delivery methods.

Noggin is necessary to start the hair growth phase in skin after birth.

PrEP for HIV is less effective in transgender women mainly due to low adherence to the treatment.

Interferon alfa-2a is effective for treating cutaneous T cell lymphoma but has significant side effects.

The Multi-Organ-Chip improves the growth and quality of skin and hair in the lab, potentially replacing animal testing.

Scientists have found a way to create hair follicles from skin cells of newborn mice, which can grow and cycle naturally when injected into adult mouse skin.

Overexpression of activin A in mice skin causes skin thickening, fibrosis, and improved wound healing.

Calcium affects where root hairs grow, but other unknown factors determine their growth direction.