2 citations
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January 2023 in “Frontiers in Veterinary Science” This study found that although Stephanofilaria infection worsens buffalo fly lesion severity, other factors like bacterial infection and hypersensitivity to buffalo fly feeding also play significant roles.
6 citations
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January 2010 in “Journal of Biochemical and Molecular Toxicology” This study found that the ID2 gene was highly expressed in bulge-derived keratinocytes when exposed to contact sensitizers and may serve as a marker to distinguish sensitizers from irritants during in vitro testing.
7 citations
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January 2002 in “PubMed” This study observed significant skin changes, including epidermal thickening and pleomorphic keratinocytes, in rats after subchronic UVB irradiation, highlighting specific reactions in the dorsal skin.
1 citations
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March 2024 in “PubMed” This case report describes an adult female who developed localized hair loss on her scalp two months after tick bites, illustrating tick bite alopecia's distinct patterns and highlighting the need to consider ticks as a possible cause of such hair loss.
28 citations
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September 2008 in “Current Pharmaceutical Design” This review discusses hypersensitivity reactions to anticoagulants like ASA and heparins, highlighting their rare but potentially life-threatening nature, and emphasizes the need for meticulous allergy testing to find safe alternatives.
In this case study, an 80-year-old woman developed lichen planus pigmentosus inversus after receiving multiple intra-articular injections of a homeopathic preparation, suggesting a possible link, though causality remains speculative.
13 citations
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March 2019 in “Pharmacology Research & Perspectives” This study analyzed CADR reports in Singapore, finding nonsteroidal anti-inflammatory drugs, antibiotics, and iohexol frequently associated with serious skin reactions like rash and angioedema, with trends varying by demographics.
2 citations
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October 2022 in “Current Allergy and Asthma Reports” This review outlines the various adverse reactions to biologic therapies in Allergy/Immunology, emphasizing the clinical and management challenges due to overlapping reaction phenotypes and the need for more refined diagnostic and management strategies.
December 2023 in “PubMed” This study highlights that homemade topical herbal preparations, although popular for their perceived safety, may lead to allergic reactions, notably with Mediterranean herbs, and advises cautious use, particularly for allergy-prone individuals.
6 citations
,
April 2012 in “Lasers in surgery and medicine” This study observed that persistent urticaria is a rare side effect of laser epilation, potentially linked to a hypersensitivity reaction in patients with allergies.
16 citations
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April 2000 in “Contact dermatitis” In this report, a 19-year-old Japanese man experienced severe and prolonged urticarial reactions following treatment with diphenylcyclopropenone for alopecia universalis, emphasizing the need for caution with potent sensitizers.
November 2025 in “Journal of Investigative Dermatology” Keloid fibroblasts cause itch and pain by releasing more histamine.
3 citations
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January 2014 in “The Journal of Dermatology” This letter discusses a case of hapten-induced lymphadenosis benigna cutis following sensitization with squaric acid dibutylester for treating alopecia areata and reports no new clinical results.
8 citations
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January 2007 in “International journal of experimental pathology” This study observed that hairless HRS/J mice were resistant to Bacillus anthracis infection at the skin's surface, suggesting resistance may be due to increased dermal neutrophils rather than non-functional hair follicles.
12 citations
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June 2010 in “Journal of dermatology” This study found that hyperpigmentation following contact immunotherapy for severe alopecia areata may indicate poor treatment responsiveness and aligns with characteristics of pigmented contact dermatitis.
March 2023 in “International Journal of Dermatology” This case report identifies a 51-year-old woman whose nonpruritic urticated rash was an initial presentation of systemic lupus erythematosus, highlighting the importance of comprehensive serological evaluation and biopsy for accurate diagnosis.
7 citations
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May 2008 in “Journal of Veterinary Internal Medicine” This case report describes a cat suspected of experiencing systemic vasculitis as an idiosyncratic hypersensitivity reaction to fenbendazole, marking it as the first documented case in cats of this rare adverse reaction.
14 citations
,
November 1987 in “Journal of The American Academy of Dermatology” A woman developed a severe skin reaction called toxic epidermal necrolysis after taking the antibiotic cephalexin.
7 citations
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July 1990 in “Journal of the American Academy of Dermatology” This case report describes a patient who developed severe alopecia and a rash after increasing captopril dosage, which resolved upon discontinuing the medication.
April 2017 in “Journal of Investigative Dermatology” In laboratory tests and mouse models, this study found that the novel IPC analog SIG-1451 may offer potent anti-inflammatory effects for treating allergic skin inflammation, potentially outperforming some current therapies in specific inflammatory phases.
July 2025 in “Indian Dermatology Online Journal” In this case report, researchers documented a rare instance of trans-epidermal elimination of insulin formulation in a 45-year-old woman with diabetes, suggesting that insulin or its excipients may have caused a granulomatous reaction leading to skin lesions at injection sites and impaired diabetes control.
October 2020 in “Our Dermatology Online” This case report highlights how chronic bacterial folliculitis may contribute to persistent inflammation in lichen simplex chronicus and emphasizes the value of DIF and IHC in diagnosing obscure cases.
This study found that subcutaneous administration of Botulinum toxin type A significantly reduced histamine-induced itch intensity and neurogenic inflammation in human skin compared to saline.
In this case study, a 70-year-old male with lymphoid variant hypereosinophilic syndrome presented with rare isolated pulmonary involvement, which improved with prednisone treatment.
36 citations
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June 2015 in “International journal of toxicology” This study established a new mouse model for TCE-induced skin sensitization and reported that proinflammatory cytokines TNF-α, IFN-γ, and IL-2 significantly contribute to this sensitization process.
2 citations
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January 2019 in “Annals of dermatology/Annals of Dermatology” This case report highlights a rare instance of permanent hair loss caused by an allergic reaction to a mesotherapy mixture containing triamcinolone acetonide, suggesting that hypersensitivity reactions to such mixtures are possible.
April 2015 in “Journal of the American Academy of Dermatology” This case study suggests that the most likely diagnosis for the patient with a pink, scaling rash is secondary syphilis.
9 citations
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April 2023 in “Experimental Dermatology” This study found that adding allergen immunotherapy to conventional treatment may reduce relapse-related hair loss in house dust mite-allergic alopecia areata patients over a 3-year period.
1 citations
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October 2013 in “The Journal of Dermatology” This letter to the editor discusses the immune response related to hair loss in a case of atypical drug-induced hypersensitivity syndrome but reports no new research findings.
January 2024 in “Pediatric rheumatology online journal” In this case report, the authors describe a child and his mother with a heterozygous STING variant linked to SAVI, who exhibited atypical disease courses and varying organ involvement, underlining the diverse clinical manifestations of SAVI.