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This review highlights the association between gender-affirming hormone therapy and increased cardiovascular risk among transgender individuals, emphasizing the need for cardiovascular-focused clinical management and further research to inform and educate both clinicians and patients.

The woman likely died from acute arsenic poisoning, not chronic exposure.

This study found that combining low-dose spironolactone with metformin improved insulin resistance in PCOS patients more effectively than using either drug alone.

This study found that incorporating PCL-based nanoscaffolds into liver spheroids enhances their viability and liver-specific biofunctionality, suggesting these scaffolds improve the model's potential for preclinical drug screening by increasing sensitivity to acetaminophen toxicity compared to traditional methods.

Among cultured sebocytes, this study found that bilobetin significantly inhibited lipid production induced by IGF-1, suggesting potential for use in acne treatment.

This study found that Greek women with classic PCOS phenotypes have a higher risk of metabolic syndrome and impaired glucose homeostasis compared to those with newer PCOS phenotypes.

This article reviews the genetic research on male androgenetic alopecia, highlighting that over 300 associated risk variants have been identified, with unclear mechanisms of action.

This case report indicates that HAIR-AN syndrome can lead to severe hyperandrogenism with virilisation signs in women after excluding tumoral causes and identifying signs of insulin resistance.

In this study, insulin resistance was observed at similar rates in non-obese women with idiopathic hirsutism, those with PCOS, and healthy controls.

This study found that women with androgenetic alopecia were more insulin resistant than healthy controls, suggesting the use of beta cell function and insulin sensitivity indices to measure insulin resistance in this population.

This study found that insurance coverage for cranial hair prostheses in patients with alopecia areata is generally inadequate, adding to their financial and psychological burdens.

This study found that the INSR His1058 C/T SNP does not increase the risk of developing PCOS among Kashmiri women.

This study found that insect wax can significantly promote hair growth in mice in a way that is comparable to minoxidil, likely due to the upregulation of VEGF expression.

This study found that acanthosis nigricans in the knuckles correlates with higher insulin and HOMA-IR values, potentially serving as an early, accessible marker for insulin resistance even without excess weight.

This study found that metformin treatment improved clinical outcomes in Taiwanese women with polycystic ovary syndrome, notably in overweight and insulin-resistant patients.

This study reports that low levels of HDL cholesterol and IGF-1 were associated with a higher risk of hair loss in middle-aged women, but causal relationships remain uncertain.

This study found that acanthosis nigricans and skin tags in nondiabetic, obese patients were significantly associated with higher insulin levels, suggesting they may serve as clinical markers of hyperinsulinemia.

In this study, topical tacrolimus 0.1% ointment applied to mice skin decreased Vegf and Igf-1 mRNA levels during late anagen but did not alter hair cycling or skin appearance compared to untreated skin.

This study found that improved testosterone measurement using LC-MS/MS in women with PCOS revealed a stronger correlation between hyperandrogenism and insulin resistance than previously detected.

This review indicates promising potential for cinnamon supplementation to improve metabolic outcomes in PCOS, but more clinical trials with higher doses and longer durations are needed to confirm these effects.

This paper explores the mechanisms causing depression in women with PCOS and suggests that lifestyle modifications, such as dietary changes and weight loss, as well as cognitive behavioral therapy and antidepressants, can help manage PCOS-induced depression.

This study found that women with PCOS had higher body fat and worse insulin resistance than non-PCOS women, with body composition influencing metabolic profiles independently of PCOS status.

This review suggests systemic changes in polycystic ovary syndrome may increase the risk of neurodegeneration, potentially linking it to Alzheimer's disease through common pathways affecting tryptophan metabolism.

This study found that among women with polycystic ovary syndrome, insulin resistance was more strongly associated with cardio-metabolic abnormalities than β-cell dysfunction, and they showed different correlations with obesity.

This study found that ferritin levels were positively associated with insulin resistance in non-diabetic Korean men and postmenopausal women, but not in premenopausal women.

This study found that thyroid volume was increased in PCOS patients with insulin resistance, with potential influences from TSH and LH levels on these changes.

This study suggests a relationship between insulin resistance and androgenetic alopecia in women, independent of hyperandrogenemia.

Different types of polycystic ovary syndrome show varying levels of insulin resistance, with the 'PHO' type being the most insulin resistant.

In this study, testosterone and finasteride were found to increase insulin and zinc levels while decreasing chromium levels in male adult rats, suggesting potential effects on the glucose cycle.

This study found that applying deer antler extract to rat skin wounds enhanced hair growth and increased IGF-I expression, suggesting potential use in hair growth products.