October 2015 in “Elsevier eBooks” Pramipexole can cause side effects like dizziness, sleepiness, hallucinations, and low blood pressure, and it's important to educate patients and keep doses low.
3 citations
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March 2012 in “Arab Journal of Urology” This study found that cromakalim and pinacidil significantly inhibited porcine detrusor muscle contractions, suggesting these ATP-sensitive potassium channel openers may have potential in treating certain bladder diseases.
47 citations
,
November 1982 in “Journal of Cardiovascular Pharmacology” Nitrendipine and nifedipine effectively block muscle contractions, while papaverine relaxes them and minoxidil needs high amounts to work.
15 citations
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November 1994 in “International Journal of Dermatology” This study found that while the combination of oral propranolol and intradermal injections in guinea pigs led to psoriasiform changes, it did not fully mimic psoriasis.
January 1983 in “Side effects of drugs annual” This chapter reviews adverse effects of anti-anginal and beta-blocker drugs, stating that starting a beta-blocker may temporarily affect driving ability, but it reports no new clinical findings.
December 2015 in “Vascular Pharmacology” Prasugrel is better than clopidogrel at preventing heart damage and improving blood flow in small heart vessels during heart artery procedures.
1 citations
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October 1974 in “Postgraduate medicine” New drugs like clonidine and prazosin show promise for treating high blood pressure despite some side effects.
June 2025 in “Experimental and Сlinical Urology” This research found that the new combination drug Predstanormix Duo, with dutasteride and tamsulosin, is bioequivalent to established treatments for benign prostatic hyperplasia, showing similar pharmacokinetics and safety, potentially improving treatment availability and adherence in high-risk patients.
January 2004 in “Headache” This study found that two-thirds of patients with persistent chronic daily headache showed significant improvement with divalproex sodium treatment, although common side effects included weight gain, tremor, hair loss, and nausea.
August 2002 in “Inpharma Weekly”
November 2006 in “Reactions Weekly” A woman's hair grew back after she stopped taking the Parkinson's disease medication pramipexole.
Minoxidil can cause hair growth as a side effect.
June 1982 in “Reactions (Auckland)” Metoprolol and propranolol may cause hair loss.
102 citations
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September 1977 in “The Lancet” Minoxidil with propranolol and diuretics lowers blood pressure but causes fluid retention and hair growth.
May 2021 in “Letters in Applied NanoBioScience” This study used computational methods to identify pranlukast and mirabegron as promising candidates for repurposing against diabetes due to their good binding interactions with the DPP-IV target.
14 citations
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October 2006 in “Journal of The American Academy of Dermatology” This report highlights a case where a woman's use of the dopamine agonist pramipexole for Parkinson's disease was associated with hair loss, which improved after discontinuing the drug.
48 citations
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January 2020 in “Cochrane Database of Systematic Reviews” This study found that serlopitant may reduce pruritus intensity compared to placebo in patients with chronic pruritus of unknown origin, though evidence is of low certainty and effects on other outcomes are unclear.
September 2020 in “Scientific periodicals of Ukraine” This study found that the combination therapy of Flosin and Prostamol Uno over nine years was well tolerated and equally effective in managing benign prostatic hyperplasia symptoms as the combination of doxazosin and finasteride, with fewer adverse events reported.
January 2008 in “Journal of Medicinal Chemistry” This study suggests that finasteride may inhibit the enzyme phenylethanolamine N-methyltransferase, which could contribute to its sexual and psychological side effects.
September 2004 in “Inpharma Weekly” This abstract details known indications, categories, and potential reactions for various drugs, including anorexiants, estrogens, NSAID analgesics, cardiac glycosides, and migraine preventives, without reporting new clinical results.
65 citations
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October 2008 in “Journal of Neuroendocrinology”
9 citations
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March 1989 in “The BMJ” Adding diltiazem to a beta blocker can cause dangerously slow heart rates.
11 citations
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January 2020 in “Micro and Nanosystems” This study found that transethosomal gel loaded with propranolol hydrochloride prolonged drug release and increased peak plasma concentration compared to an oral tablet, suggesting a promising alternative for delivery.
January 2023 in “Journal of clinical pharmacy and therapeutics” This study found that isoliensinine, a natural compound identified from a database, effectively prevented stress-induced hair greying in mice by blocking β-2 adrenergic receptors on melanocyte stem cells in hair follicles.
February 2006 in “Inpharma Weekly” 24 citations
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December 2020 in “Kardiologiia” This study found that combining bromhexine and spironolactone was effective in improving clinical outcomes and reducing viral load or hospitalization duration in patients with mild to moderate COVID-19.
June 2023 in “Frontiers in Cardiovascular Medicine” This review identified two promising therapeutic targets for drug repurposing to treat refractory angina in patients with angina pectoris without obstructive coronary artery disease: endothelin-1 receptor blockers and soluble guanylate cyclase stimulators.
18 citations
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October 2010 in “Bioorganic & Medicinal Chemistry Letters” This study found that a new hybrid compound designed from finasteride and epristeride was a potent inhibitor of 5α-reductase with a mechanism similar to finasteride.
August 2026 in “International Journal of Dermatology” This article discusses the availability of data from TriNetX for research purposes and reports no new findings.