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Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.

Scalp itching is common and hard to diagnose due to the complex nerve structure of the scalp.

TLR4 is important in aging-related diseases and could be a new treatment target.

Zinc is crucial for skin health and treating various skin disorders.

The research suggests immune system changes and specific gene expression may contribute to male hair loss, proposing potential new treatments.

Dupilumab is being tested for many new skin, respiratory, and gastrointestinal conditions.

Men are more likely to have severe respiratory viral infections like COVID-19 due to hormonal and genetic differences, while women generally have stronger immune responses.

Extra virgin olive oil may boost the immune system and help fight infections like COVID-19.

Adult skin quickly reacts to short-term environmental and internal stress, leading to various skin issues and the need for protective measures.

Dying cells can help with faster healing and new hair growth by releasing a growth-promoting molecule.

Understanding hair follicle biology and stem cell control could lead to new hair loss treatments.

Hormonal therapies are safe and effective for treating acne in female adolescents, with specific treatments for those with endocrine disorders.

Men and women get COVID-19 at similar rates, but men tend to get sicker and have a higher risk of dying, while women usually have stronger immune responses and vaccine reactions.

Metformin, a diabetes drug, may help prevent and treat various cancers, but more research is needed.

Testosterone's effects on COVID-19 are unclear and need more research.

DHT may reduce inflammation caused by certain bacteria in skin cells.

Cholesterol-related compounds can stop hair growth and cause inflammation in a type of scarring hair loss.

The document concludes that understanding how the skin's immune system and inflammation work is complex and requires more research to improve treatments for skin diseases.

Hidradenitis suppurativa is a skin disease caused by the breakdown of the skin's natural immune barriers, especially around hair follicles.

Blocking IL-17 can reduce skin inflammation in a mouse model of pityriasis rubra pilaris.

Inflammation linked to the immune response may play a role in causing various types of hair loss.

Skin stem cells remember past inflammation, helping them respond better to future injuries and possibly aiding in treating skin issues.

A specific immune response helps control mite populations on the skin, maintaining healthy hair follicles.

Sex hormones may be linked to inflammation in Hidradenitis Suppurativa.

Skin fat plays a key role in immune defense and healing beyond just storing energy.

Nitric oxide is important for skin functions and both helps protect against and contributes to skin inflammation and sensitization.

Epiduo® is an effective first-line acne treatment that reduces inflammation and combats antibiotic resistance.

We now understand more about what causes acne and this could lead to better, more personalized treatments.

IL-1 family cytokines are crucial for skin defense and healing, but their imbalance can cause skin diseases.

Seborrheic dermatitis and dandruff are often treated with antifungal and anti-inflammatory medications, which can reduce symptoms and yeast growth on the scalp.