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Overexpression of HDGF in melanocytes does not cause cancer.

Distinct β-catenin patterns are linked to cell growth, not cell death, in lung cancer.

Histone demethylases play a key role in the development of many diseases and may be targets for treatment.

Hair follicles produce IL-7, which is essential for certain skin lymphoma cells to survive.

The article concludes that while we understand a lot about how melanocytes age and how this can prevent cancer, there are still unanswered questions about certain pathways and genes involved.

Deleting the Trf1 protein in mice is safe and may help prevent cancer without major side effects.

Hair follicle-derived IL-7 and IL-15 are crucial for maintaining skin-resident memory T cells and could be targeted for treating skin diseases and lymphoma.

PTEN helps control the number and health of skin stem cells by working with the protein BMAL1.

Understanding how epigenetic regulation affects stem cells is key to cancer insights and new treatments.

Short telomeres contribute to aging and cancer, and while telomerase can delay aging, it may also promote cancer.

CYLD mutations cause a variety of skin tumors with symptoms starting around age 16, and treatments are currently limited.

Budesonide and N-acetylcysteine reduced tumors and alopecia in mice, regardless of FHIT gene status.

Understanding phenotypic plasticity is crucial for developing effective cancer therapies.

MicroRNAs are crucial for controlling skin development and healing by regulating genes.

New treatments targeting skin stem cells show promise for skin repair, anti-aging, and cancer therapy.

Air pollution worsens skin diseases and aging by causing inflammation and oxidative stress.

Mice that can regenerate tissue have cells that pause in the cell cycle, which is important for healing, similar to axolotls.

Removing p16INK4a from skin cells can lead to faster and more clumped growth, which might help with hair growth.

The research showed how melanocytes develop, move, and respond to UV light, and their stem cells' role in hair color and skin cancer risk.

Non-surgical procedures can help reduce wrinkles and stimulate skin repair by understanding skin aging at the molecular level.

Maintaining DNA health in stem cells is key to preventing aging and tissue breakdown.

Certain transcription factors are key in controlling skin stem cell behavior and could impact future treatments for skin repair and hair loss.

The skin protects the body and is constantly renewed by stem cells; disruptions can lead to cancer.

Minoxidil and ATRA together boost hair growth more effectively than minoxidil alone.

Eating less can slow aging and help keep stem cells healthy by cleaning out damaged cell parts.

Troxerutin helps protect skin cells from oxidative stress and may be good for treating hair loss.

Actinic keratosis can lead to skin cancer, is more common in fair-skinned people, and can be reduced with sunscreen and treated effectively.

Skin aging is caused by stem cell damage and can potentially be delayed with treatments like antioxidants and stem cell therapy.

Eph receptors and ephrins may be promising targets for treating diseases, but more understanding is needed for effective and safe therapies.

In vivo lineage labelling is better than in vitro methods for identifying and understanding stem cells.