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Epidermal stem cells are diverse and vary in activity, playing key roles in skin maintenance and repair.

Hair follicle stem cells are key for hair and skin regeneration, can be reprogrammed, and have potential therapeutic uses, but also carry a risk of cancer.

Fibroblast Growth Factors (FGFs) are important for tissue repair and regeneration, influencing cell behavior and other factors involved in healing, and are crucial in processes like wound healing, bone repair, and hair growth.

Keratinocytes help heal skin wounds by interacting with immune cells and producing substances that kill pathogens.

Delta opioid receptors help regulate touch sensation by reducing neurotransmitter release in the spinal cord.

The niche environment controls stem cell behavior and plasticity, which is important for tissue health and repair.

Protoporphyrin IX is useful in cancer treatment but can cause health problems if not properly regulated.

Hair follicle melanocytes die during hair regression.

Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.

The document concludes that while significant progress has been made in understanding skin biology and stem cells, more research is needed to fully understand their interactions with their environment.

Flutamide rarely causes liver toxicity in prostate cancer patients.

Ruby laser pulses best destroy hair follicles during the growth phase and effectiveness varies with laser intensity; melanin is key for targeting, and timing treatments can improve results.

Shift work disrupts the body's natural clock, leading to health problems.

UVB exposure in human skin causes macrophages to produce more IL-10 and less IL-12, leading to immunosuppression.

Low-oxygen conditions and ECM degradation products increase the healing abilities of perivascular stem cells.

Hair patterns in mice are controlled by both a global system dependent on Fz6 and a local self-organizing system.

The Wnt/β-catenin pathway is important for tissue development and has potential in regenerative medicine, but requires more research for therapeutic use.

Sericin hydrogels heal skin wounds well, regrowing hair and glands with less scarring.

Teriflunomide is safe and tolerable for treating relapsing-remitting multiple sclerosis, with manageable side effects.

Nuclear hormone receptors play a significant role in skin wound healing and could lead to better treatment methods.

Elental is a good long-term treatment for Crohn's disease, similar to 6-mercaptopurine but with fewer side effects.

Skin fat has important roles in hair growth, skin repair, immune defense, and aging, and could be targeted for skin and hair treatments.

Skin stem cells maintain and repair the outer layer of skin, with some types being essential for healing wounds.

Stem cells help repair tissue mainly by releasing beneficial substances, not by replacing damaged cells.

Adipose-derived stem cells can help treat hair loss.

Melatonin may reduce skin damage caused by X-rays in rats.

Skin fat plays a key role in immune defense and healing beyond just storing energy.

A hair wrapped tightly around an infant's toe caused severe damage, requiring early removal and possibly surgery to prevent worse outcomes like amputation.

Understanding how melanocyte stem cells work could lead to new treatments for hair graying and skin pigmentation disorders.

A special hydrogel helps heal skin without scars and regrows hair.