October 2021 in “QJM: An International Journal of Medicine” The study evaluated the efficacy of Platelet-Rich Plasma (PRP) therapy on androgenic alopecia in male albino rats. Eighteen rats were divided into three groups: control, testosterone, and PRP. The PRP group showed a significant increase in the number of anagen hair follicles and epidermal thickness, and a decrease in telogen hair follicles, compared to the control and testosterone groups. Immunohistochemical analysis revealed an increase in Ki 67 positive basal epidermal cells in the PRP group. The results suggest that PRP injections may have a positive therapeutic effect on androgenic alopecia.
April 2018 in “Selçuk Üniversitesi Tıp Fakültesi dergisi” The study investigated the development of hyperalgesia in patients with androgenetic alopecia treated with autologous platelet-rich plasma (PRP). Ten male patients aged 25-35 received PRP injections in the scalp over a year, experiencing increased pain sensitivity after each application, with the highest hyperalgesia observed in the first year post-treatment (p < 0.05). Hair density increased by 6.4%, 9.4%, 21%, and 27.6% at 1, 2, 6, and 12 months, respectively. The study concluded that repeated PRP injections could cause hyperalgesia, potentially due to growth factors in PRP, and recommended further research to understand this phenomenon.
64 citations,
January 2009 in “Canadian Journal of Gastroenterology” Interferon and ribavirin can cause serious skin reactions and other health issues.
47 citations,
September 2013 in “Biology of blood and marrow transplantation” Mice with human fetal thymic tissue and stem cells developed symptoms similar to chronic graft-versus-host disease.
10 citations,
June 2012 in “Dermatologica Sinica” A patient with PPP had rare skin reactions to adalimumab, which improved after stopping smoking and continuing acitretin.
9 citations,
October 2013 in “Journal of Investigative Dermatology” The OVOL1 gene, controlled by β-catenin, is crucial for creating hair follicles.
8 citations,
June 2023 in “Journal of clinical medicine” Nanofat shows promise for facial rejuvenation and treating skin issues but needs more research for long-term safety.
6 citations,
May 2021 in “Aesthetic Surgery Journal” The study investigated the effects of different concentrations of platelet-rich plasma (PRP) on hair density and diameter in 8 subjects with androgenetic alopecia (AGA). It found that higher cell number PRP significantly improved hair density and diameter compared to lower cell number PRP and placebo. Both treatments were safe and well-tolerated, with no significant adverse events reported. The study concluded that higher cell number PRP might offer greater benefits for treating AGA, though further research is needed to confirm these findings.
5 citations,
February 2022 in “Journal of the European Academy of Dermatology and Venereology” The Covishield COVID-19 vaccine caused skin-related side effects in 1.23% of the people vaccinated in the study from India.
4 citations,
January 2022 in “Yonsei Medical Journal” Microneedles are a promising method for drug delivery, offering efficient and convenient alternatives with fewer side effects.
3 citations,
September 2023 in “Advanced science” A new vaccine using a porous scaffold boosts immunity and protects against the flu better than traditional methods.
3 citations,
May 2017 in “Heliyon” Wound healing can help prevent hair loss from chemotherapy in young rats by increasing interleukin-1β signaling.
3 citations,
May 2013 in “International journal of molecular sciences” Epidermal stem cells show promise for treating orthopedic injuries and diseases.
2 citations,
January 2023 in “Frontiers in Oncology” Mild oxidative stress can prevent hair loss from chemotherapy.
2 citations,
June 2021 in “Cosmoderma” Platelet-rich plasma (PRP) shows promise in skin and hair treatments but results vary with preparation methods.
1 citations,
July 2023 in “Journal of Clinical Medicine” Different causes of beard hair loss have various treatments, including medications, lifestyle changes, and procedures to stimulate hair growth.
1 citations,
December 2017 in “Journal of clinical and investigative dermatology” Platelet-Rich Plasma (PRP) treatment can significantly increase hair count and thickness in people with Androgenetic Alopecia (AGA) with minimal side effects.
August 2024 in “Journal of Cosmetic Dermatology” Injectable treatments can effectively and safely improve hair growth in adults with androgenetic alopecia.
April 2024 in “Skin health and disease” Injecting fillers in the temple can cause serious complications, but the damage can be treated if managed properly.
January 2024 in “International Journal of Medical Sciences” New regenerative medicine-based therapies for hair loss look promising but need more clinical validation.
November 2023 in “Journal of cosmetic dermatology” Fat transplants using a patient's own fat can rejuvenate and repair tissues effectively.
November 2023 in “Advanced Science” A specific hair protein variant increases the spread of breast cancer and is linked to worse survival rates.
August 2023 in “Journal of Cosmetic Dermatology” Higher concentration of botulinum toxin A is safe and effective for treating hair loss in men and women.
June 2023 in “Skin Research and Technology” Using platelet-rich plasma injections and 5% minoxidil topically can safely and effectively treat mild-to-moderate male pattern baldness.
June 2023 in “Journal of Cosmetic Dermatology” The treatment combining platelet-rich plasma and a non-cross-linked hyaluronic acid compound significantly improved hair density and reduced bald areas in women with androgenetic alopecia, and it's safe with only mild side effects.
March 2023 in “Scientific Reports” Using focused ultrasound on the brain can help epilepsy medicine work better in rats.
January 2023 in “International Journal of Trichology” PRP therapy for hair loss is safe but its effectiveness is doubtful.
May 2015 in “Hair transplant forum international” The article concludes that PRP might help with hair loss, but more detailed research is necessary.
July 2023 in “International journal of trichology” Platelet-rich Plasma (PRP) helps treat hair loss effectively, especially when prepared using the double-spin method.
321 citations,
January 2012 in “Cell stem cell” TGF-β2 helps activate hair follicle stem cells by counteracting BMP signals.